P34 24-Hour Ambulatory Brachial Versus Aortic Systolic Blood Pressure: Relationship with Left Ventricular Mass Significantly Differs. Pooled Results from the International 24 Hour Aortic Blood Pressure Consortium (i24ABC)
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- 10.2991/artres.k.191224.066How to use a DOI?
- Abstract
Background: There is evidence of a closer relation between 24 hour aortic systolic blood pressure (aSBP) and left ventricular mass (LVM) compared with 24 hour brachial SBP. However, sample sizes are relatively small and there is some inconsistency in findings. We sought to address this by pooling data from 16 centers in Asia, Europe and Latin America to determine the relationship between LVM and brachial office, as well as brachial and aortic 24 hour ambulatory SBP.
Methods: In all centers, brachial and aortic SBP was measured with the same validated oscillometric device, using a transfer function for aortic pressure, and mean/diastolic pressure calibration. LVM was determined by echocardiography.
Results: We studied 2092 participants (972 women) with a mean age of 52 years. Mean brachial office BP was 137/84 mmHg, and mean 24 hour bSBP and aSBP was 126 [118;134] and 131 [120;137] mm Hg, respectively. Mean LVM indexed to body surface area was 88.4 g/m2, and 27.2% of participants had left ventricular hypertrophy (LVH). The correlation coefficients between LVM and brachial office SBP, 24 hour bSBP, and 24 hour aSBP were 0.24, 0.35, and 0.43, respectively (p < 0.001 for differences). The areas under the curve for prediction of LVH were 0.62, 0.67, and 0.70 for brachial office SBP, 24 hour bSBP, and 24 hour aSBP, respectively (p < 0.001 for differences).
Conclusion: In this pooled analysis of international data, we demonstrate that aortic ambulatory SBP, measured with an oscillometric cuff, shows a significantly closer association with hypertensive cardiac organ damage (left ventricular mass and hypertrophy) than brachial office/brachial ambulatory systolic blood pressure.
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- © 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
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- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
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TY - JOUR AU - Siegfried Wassertheurer AU - Athanase Protogerou AU - James Sharman AU - Enrique Rodilla Sala AU - Piotr Jankowski AU - Maria Lorenza Muiesan AU - Cristina Giannattasio AU - Bernhard Hametner AU - Jose Maria Pascual AU - Robert Zweiker AU - Antonio Argyris AU - Anna Paini AU - Ian Wilkinson AU - Danuta Czarnecka AU - Massimo Salvetti AU - Alessandro Maloberti AU - Carmel McEniery AU - Yan Li AU - Janos Nemcsik AU - Giacomo Pucci AU - Cornelia Ablasser AU - Jacques Blacher AU - Alexandre Valleé AU - Alejandro de la Sierra AU - Yi Zhang AU - Hongwei Ji AU - Barry McDonnell AU - Marco Mota AU - Annelise Paiva AU - Andrea Brandao AU - Thomas Weber PY - 2020 DA - 2020/02/15 TI - P34 24-Hour Ambulatory Brachial Versus Aortic Systolic Blood Pressure: Relationship with Left Ventricular Mass Significantly Differs. Pooled Results from the International 24 Hour Aortic Blood Pressure Consortium (i24ABC) JO - Artery Research SP - S75 EP - S75 VL - 25 IS - Supplement 1 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.191224.066 DO - 10.2991/artres.k.191224.066 ID - Wassertheurer2020 ER -