Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

Session: Pharmaceutical Engineering

14 articles
Proceedings Article

The Phase of Oscillation in Cortical Network and Its Relationship with Firing Rate and Neuronal Activation

Daming WANG, Yaoru SUN
Gamma-band neuronal oscillation and synchronization (30-90 Hz) are frequently observed in several cortical and subcortical circuits and are supposed to be involved in a variety of cognitive functions. The phase of the oscillation, referred to as one aspect of communication through coherence (CTC) hypothesis,...
Proceedings Article

Spectrophotometric Determination of Penicillamine in Pharmaceutical Sample using Fe(III)-Tiron System

Xinrong WEN, Changqing TU
Hydrosulfuryl(-SH) in penicillamine molecule can reduce Fe(III) to Fe(II), then using tiron as chromogenic reagent of Fe(III), and the content of penicillamine is determinated indirectly through determinating the surplus content of Fe(III) in the system. An accurate fast spectrophotometric method for...
Proceedings Article

Chitosan Derivative Nanoparticles as Prolonged Releasing Drug Carriers

Bohua FENG, Liufen PENG
Ricinoleic acid grafted amphiphilic carboxymethy chitosan (CMC-g-RA) was synthesized as a carrier to load botanical drug rotenone (Rot). Then Rot/CMC-g-RA water dispersion in nanoscale was prepared, whose shape, zeta potential, loading efficiency and outdoor stability were characterized accordingly....
Proceedings Article

Research and Implementation of Discovering and Recommending Experts in Medical Community-Based Q&A

Lan FANG, Yu FANG
With the continuous development of the Internet, community-based Q&A (CQA) system has become an effective platform for people to access online information and help. People can submit their own question in CQA and get answers from others. There will be an enormous amount of questions all the time, and...
Proceedings Article

Prognostic Analysis of The Effects of Starvation and Overfeeding on Children

Le KANG, Mingsan MIAO
By comparing the effects of excess nutrients and malnutrition on the body of children, It is concluded that the harm to children's body caused by excessive nutrition is more than that of malnutrition, and overnutrition is also a performance of malnutrition. The causes of obesity in children, the present...
Proceedings Article

Experimental Study on Carbonation Treatment

Zhenwei YU, Kunjie CHEN, Zhao LI, Wang YU
The scope of Chinese medicine residue and utilization is relatively narrow, and the harmless processing technology needs to be systematized. Since its feasibility is still being questioned by people, this research discusses the properties of the Chinese medicine residue carbonation characteristics and...
Proceedings Article

Progress in Research on Small Molecules as Gene-targeted Drugs

Yanli WANG, Sijia WANG, Jun XU, Wen ZHANG
The findings of effective targets and the identification of target binding molecules are two key points in drug discovery. The complete human genome and their rapid increase in structural and functional information led to new possibilities for diagnosis and therapy of diseases, using gene-targeted drugs....
Proceedings Article

A Recurrence Quantification Analysis of Traditional Chinese Medicine Pulse and Its Application in Assessment of Coronary Artery Disease

Rui GUO, Yiqin WANG, Jianjun YAN, Haixia YAN
Purpose: This study was conducted to illustrate that pulse diagnosis of traditional Chinese medicine (TCM) was useful in the assessment of coronary artery lesions in patients with Coronary Heart Disease (CHD). Methods: By using phase-space reconstruction, one-dimensional pulse signals of participants...
Proceedings Article

Melittin: A Key Composition of Honey Bee Venom with Diverse Pharmaceutical Function

Sheng HUANG, Jianhua WANG, Xiaozhong WANG, Chenghong LI
Melittin is the main toxic component in the the honey bee venom. It is a cationic, lytic peptide constituted by 26 amino acid residues. This peptide is an amphoteric molecule which the carboxy-terminal region is hydrophilic and the amino-terminal region is hydrophobic due to the presence of a series...
Proceedings Article

Quantitative Analysis of Ketoprofen Enantiomers by Liquid Chromatography/Electrospray Ionization-Mass Spectrometry

Fen YANG, Dongri JIN
A enantioselective and sensitive liquid chromatography/electrospray ionization-mass spectrometry (LC/ESI-MS) method is developed for the quantitative analysis of ketoprofen (KET) enantiomers based on a straightforward one-pot two-step stable isotope-coded derivatization of KET with a chiral derivatization...
Proceedings Article

Tongue Characteristics of Different TCM Syndromes on Asthma

Sijing WANG, Zhaoxia XU, Yiqin WANG
Asthma is kind of disease affecting quality of life. Different TCM asthma types have different characteristics.TCM tongue images can be objective indexes for asthma TCM differentiation and therapeutic evaluation. More and more modern technique and analysis methods are used to discuss meaning of tongue....
Proceedings Article

Blends of Poly (L-Lactic Acid) and Glucose Prepared from Mixture Solution

Dan CAO, Qinwei GAO, Yinping ZHAO, Wei MING
Poly (L-lactic acid) (PLLA) and glucose (Glu) were respectively dissolved in N, N-dimethyl acetamide to prepare solutions. The blends of PLLA and glucose with various ratios were prepared by mixed solution method, and characterized with infrared Fourier transform spectrometry, differential scanning calorimetry,...
Proceedings Article

Crystallization of the Racemic Conglomerate and Racemic Compound of Efonidipine

Linyuan ZHU, Zhanjun LI, Yuzhen YU, Wen LI
Efonidipine is a dual blocker of T-type and L-type calcium channels with 1, 4-dihydropyridine structure attached to a phosphonate skeleton. As a chiral compound, it has a special property that can exist as a racemic conglomerate or a racemic compound based on the different crystallization conditions....
Proceedings Article

Synthesis of Dinucleoside Triphosphates Containing Antiviral Nucleoside

Rong LIU, Shanshan GONG
A general and efficient method for the synthesis of asymmetrical dinucleoside triphosphates with an antiviral nucleoside moiety has been developed. The coupling of adenosine diphosphate with antiviral nucleoside phosphoropiperidate via the DCI activation of P-N bond afforded the desired products in good...