Protective effects of malvidin and the glycosides from Vaccinium ashei on endothelial cells were investigated. The results showed that malvidin, malvidin-3-glucoside, malvidin-3-galactoside, and their mixture could defend endothelial cells from damage caused by TNF- , and inhibit monocyte chemotactic...

This study investigated effects of 2-month isomalto-oligosaccharide (IMO) supplementation on fecal colonic bacterial enzymes, bile acid metabolites, and fecal toxicity in the nursing-home residents. Twelve nursing-home residents (mean age 85.2 1.9 y. o.) participated in the placebo-controlled and diet-controlled...

Poly (lactic acid) has become a hot topic in biomedical field due to good biocompatibility and biodegradability. As an important method for synthesis of poly lactic acid materials, ring-opening polymerization of lactide catalyzed by metal complexes can achieve the controllable polymerization of lactide...

In order to accelerate the speed of titanium implant osseointegration, titanium substrates were polished by silicon carbide abrasive papers and treated by sodium hydroxide solution. The treated titanium substrates were immersed in simulated body fluid at 37 C for several days, through bio-simulated mineralization,...

Pyrolysis production and structure of molecule of high purity natural rubber (NR) were studied. Results show that there is no stretching vibration absorption peak of N-H group on 3280cm-1 and vibration compound peak of C-N group and N-H group in amide group on 1540cm-1 in high purity NR comparing to...

Thermal oxidation kinetics of raw constant viscosity natural rubber (CVNR) prepared with fresh natural rubber (NR) latex containing several difference viscosity stabilizers was studied. The comparison with the ageing characteristics of hot oxygen (hot air), ozone and light oxygen (ultraviolet light)...

Purposes: To sum up the characteristics of Chinese medicine with chrysanthemum and lay a foundation for the development of new dosage forms and the rational application of Chinese Medicine. Methods: According to the Chinese Pharmacopoeia contains chrysanthemum in the pharmaceutical dosage form, drug...

Six kinds of seaweed polysaccharides (SPSs) extracted from Laminaria japonica, Porphyra yezoensis, Gracilaria lemaneiformis, Sargassum fusiforme, Eucheuma gelatinae and Undaria pinnatifida were degraded and characterized. The sulfate group (-OSO3H) content of these polysaccharides were 21.7, 17.9, 13.3,...

To solve the problem of observing and testing the movement behavior control ability of aquatic animal robot, we have developed a double-layer multi-channel water maze device. The device is a rectangular parallelepiped structure composed of a square bottom, four rectangular side walls .The channel on...

In this paper, pepsin, trypsin and chymotrypsin were used to hydrolyze royal jelly water soluble proteins from Xinjiang Black Bee, and peptides with the molecular weight of more than 10kD, 3-10kD as well as less than 3 kD were obtained by using ultrafiltration. Through the determination of total antioxidant...

3-(2-chloro-5-fluoropyrimidin-4-yl)-1-methyl-1H-indole is an important intermediate in many bioactive compounds, such as osimertinib. In this task, a new intermediate is synthesized (a fluorine attached to the pyrimidine ring). The compound is synthesized from commercially available 1H-indole through...

4-(4-aminophenoxy)-N-propylpicoliamide 4 is an important intermediate for the synthesis of many biologically active compounds. The compound 4-(4-aminophenoxy)-N-propylpicolinamide was obtained by three simple steps to synthesis from picolinic acid. In this paper, three novel 3-phenyl-1H-pyrazole derivatives...

4-(pyrrolidin-1-ylmethyl)benzaldehyde (1) as a water-soluble aldehyde is an important intermediate for small molecule anticancer drugs. A rapid and high yield synthetic method for 4-(pyrrolidin-1-ylmethyl)benzaldehyde (1) was established in this work. The target compound was synthesized from the commercially...

(E) -3- (dimethylamino) -1- (1H-indol-3-yl) prop-2-en-1-one (4) is an important intermediate in many biologically active compounds such as osimertinib. In this work, compound (4) was synthesized through three steps, using 1H-indole as starting material. The synthetic method of 4 was optimized and can...

Diethyl 2-(2-chloronicotinoyl)malonate 3 is a nitrogen-containing water-soluble carboxylic acid as an important intermediates of small molecule anticancer drugs. In this study, this paper explored a faster and celerity method to synthesize compound 3. By using 2-chloronicotinic acid as a kind of easily...

Nitrogen-containing 4-alkoxybenzaldehyde analogues as a kind of water-soluble aldehyde are important intermediates for small molecule anticancer drugs. A rapid and high yield synthetic method for nitrogen-containing 4- alkoxybenzaldehyde analogues was established in this work. The target compound was...

Tert-butyl 4-formyl-3, 6-dihydropyridine-1(2H)-carboxylate(9) is an important intermediate for small molecule anticancer drugs. A rapid and high yield synthetic method for tert-butyl 4-formyl-3, 6-dihydropyridine-1(2H)-carboxylate was established in this work. The target compound was synthesized from...