Caries are common in early childhood. The prevalence of early childhood caries according to the American Academy of Pediatric Dentistry is 57.7%. One of the causes is Streptococcus mutans bacteria. The most effective method to prevent plaque accumulation is to brush the teeth with toothpaste. Chitosan...

The objective of this study is to evaluate the surface roughness of a nanofiller composite resin after immersion in black tea for 1, 2, 3, and 4 h. A total of 24 disk-shaped samples were fabricated from a nanofiller composite resin (Filtek Z350XT, 3M ESPE, USA) and divided into the following four test...

The aim of this research was to investigate the comparative effectiveness of ang-sana latex (P. indiscus) and chlorhexidine 0.2% against growth of S. mutans. This research was a laboratory experiment (true experimental), with a post-test only completely randomized design, consisting of four treatments:...

Sterilization is the process of destroying or eliminating all microorganisms. The aim of sterilization is to destroy every form of pathogenic microorganism includ-ing spores that might adhere to dental instruments and associated equipment. Dental instruments that come in direct contact with the human...

Tetracycline has been widely used as a periodontal support treatment since it has broad-spectrum bone tissue penetration and it can inhibit native collagen. Chi-tosan hydrogel-based tetracycline is known to have strong antibacterial effects, but the cytotoxic effects on fibroblast have yet to be studied....

The aim of this study was to investigate the activation effect of PRP using colla-gen to the synthesis of extracellular matrix in fibroblasts of the periodontal liga-ment. The PRP from the human donor was activated using collagen (collagen-activated PRP) and compared with inactivated PRP as a control...

This study was to analyze the effect of alginate based metronidazole gel in inhib-iting A. actinomycetemcomitans bacteria growth with in vitro evaluation. Algi-nate-based gel used in this study contains metronidazole 15%, 25%, and 25% metronidazole non-alginate based gel as a comparison. The bacteria...

The objective of this study is to determine the difference between A. actinomy-cetemcomitans and P. gingivalis virulence as the cause of periodontal disease. Thirty male Wistar rats were divided into six groups. Ten rats were induced by 10 ug/mL P. gingivalis lipopolysaccharides (LPS), and the other...

The objective of this study is to determine the in vitro cytotoxicity effect of chitosan hydrogel-based metronidazole on fibroblast. Chitosan hydrogel-based metronidazole(0.12%, 0.15%, 0.25%) and chitosan without metronidazole are made by dissolving lactic acid to reach a gel consistency, and then adding...