Atlantis Highlights in Chemistry and Pharmaceutical Sciences

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131 articles
Proceedings Article

Development of Augmented Reality-Based Online Learning Media to Improve Students’ Mental Models on the Topic of Environmental Pollution

Wildan, Saprizal Hadisaputra, Lalu Rudyat Telly Savalas, Baiq Dwi Laksmiwati, Supriadi
The purpose of this study was to develop online learning based on augmented reality (AR) technology related to environmental pollution and its effect on the mental model of students of the Chemistry Education Study Program, FKIP University of Mataram. The results of this study are expected as a first...
Proceedings Article

Validity of Interactive Multimedia with 3D Visualization to Practice the Spatial Visual Intelligence of Class X High School Students on Metallic Bonding Materials

Irvandar Nurviandy, Kusumawati Dwiningsih, Ahlan Riwahyu Habibi, Akhmad Fitriadi Akbar
This study aims to determine the validity of Interactive Multimedia with 3D Visualization to Train the Spatial Visual Intelligence of Class X High School Students on Metallic Bonding Materials. Validity is tested through quality of content and goals, instructional quality, and technical quality. Development...
Proceedings Article

Literature Review: Antidiabetic Activities and Phytochemical Screening of Broccoli Plants (Brassica oleracea L. Var. italica)

Alya Chairunnisa, Haryoto
Diabetes mellitus is a metabolic disease that is characterized by hyperglycemia which is closely related to pancreatic β cell dysfunction and insulin resistance. Brassica oleracea L. var. italica is a member of the Brassicaceae family which has antidiabetic properties. These effects are caused by the...
Proceedings Article

Reading, Questioning, and Answering (RQA) Strategies’: an Alternative to Empowering Undergraduate Student Thinking Abilities

Harun Nasrudin, Utiya Azizah
Reading, Questioning, and Answering (RQA) is a constructivist based learning strategy. The implementation of RQA can motivate undergraduate students to read the assigned material and have an impact on improving the understanding of learning material. This study aims to describe undergraduate students'...
Proceedings Article

Analysis of the Level of Metacognitive Awareness and Students’ Character Education Values of Eleventh-Grade Science in the Chemistry Learning Process

Aruna Akbar Zhafransyah, Supriadi, Yunita Arian Sani Anwar, Muti`ah
Chemistry learning is characterized by the study at the submicroscopic level, which includes structure, dynamics, and particle transformation, such as atoms, ions, and molecules. In addition, chemical concepts tend to be related to one another, making it difficult for students to understand. Metacognitive...
Proceedings Article

Students’ Misconceptions on Understanding Corrosion Topic by and without Analogy

Findiyani Ernawati Asih, Suhadi Ibnu, Suyono Suyono, Suhadi Suhadi
Redox reactions is spontaneous which can produce electrons flow. This condition can make corrosion of ferrum metal . The electrons flow is not observed (submicroscopic aspect), so requires visualization. Strategy for visualizing submicroscopic aspect is analogy learning. The electrons flow can be analogous...
Proceedings Article

Literature Review: Cytotoxic Activity of Pineapple (Ananas comosus L.) Against Cancer Cells

Diyenda Ainun Nida, Haryoto
Pineapple (Ananas comosus L.) is a plant in the Bromeliaceae family that has pharmacological effects such as antimicrobial, anthelmintic, diuretic, antidiabetic, and anticancer properties. This review aims to determine the anticancer activity and action mechanism of pineapple (Ananas comosus L.). The...
Proceedings Article

The Validity of Teaching Materials Oriented to Argument-Driven-Inquiry Model to Train Students’ Science Literacy

Faridatur Rofi'ah, Tukiran Tukiran, Endang Susantini
Research related to the development of teaching materials using the Argument-Driven-Inquiry model to train Students’ Science Literacy which seems not to have been done. Therefore, the purpose of this study is to produce a valid teaching materials. The developed teaching materials focused on the buffer...
Proceedings Article

Enhacing Mastery Of Students’ Concept Through Science Technology Society (STS) Approach On Chemical Equilibrium

Dwi Rahmi Putri, Leny Yuanita, Bambang Sugiarto
This study aims to determine the enhancement mastery of students' concepts after being given learning based on the Science Technology Society (STS) approach to Chemical Equilibrium. Students in class XI MIA 1 and XI MIA 2 of Senior High School 4 Sidoarjo be a subject. The data is obtained from concept...
Proceedings Article

Interactive Multimedia and Kit Implementation on Chemistry in Daily Life Topic with Writing-to-Learn Strategy for Hearing Impairment Students

Dian Novita, Sri Poedjiastoeti, Sukarmin Sukarmin, Achmad Lutfi
This research aims to describe the implementation of interactive multimedia and kits on Chemistry in Daily Life Topic. The kit consists of student activity sheet and tools and materials for experiment. Student activity sheet of chemistry on foods and chemistry on household theme each consist of four...
Proceedings Article

Iodination of Isoeugenol Compounds and Its Potential for Therapy of HER-2 Breast Cancer by Molecular Docking

Dadan Suryasaputra, Athina Mardatillah, Putri Nurfadilah
This research used the synthesis of isoeugenol with iodide to improve anticancer activity on the isoeugenol compounds as the first step in the manufacture of radiopharmaceuticals. One of the anticancer mechanisms of isoeugenol is in silico, potentially inhibiting the target molecules on the growth of...
Proceedings Article

The Effectiveness of Guided Discovery Based Learning Materials to Increase Students’ Learning Outcomes

Devi Evylia Purmawanti, Utiya Azizah, Sari Edi Cahyaningrum
This research aimed to know the effectiveness of learning materials based on guided discovery to inrease students’ learning outcomes. The research model used in this study was Research and Development (R&D), but it is only limited to the development stage, namely by conducting a trial I. Trial I was...
Proceedings Article

Effectiveness Of Learning Media Using Argument Driven Inquiry (ADI) Learning Model To Increase Students’ Learning Outcomes And Self Efficacy

Ni'mah Tukiran, Nasrudin Choirun, Harun
This research aimed to find the effectiveness of a theaching instrument in order to increase students’ self efficacy and learning outcomes using Argument Driven Inquiry (ADI) teaching instrument on the electrolyte and non-electrolyte. The test was applied to the 30 students of grade X-3 and X-4 in Senior...
Proceedings Article

Application Of Chemmo Configuration Play As A Learning Media Of Elements Periodic System

Achmad Lutfi, Rusly Hidayah, Muslela Qona'atun
This study aims to determine the effect of using the Chemmo Configuration game that has been developed based on pedagogical requirements and game requirements as a learning medium. The form of research used was Pre-Experimental Research with the design of a single group One Group Pretest-Posttest Design...
Proceedings Article

Analysis of Residual Solvents in Co-amoxiclav Coated Tablets Using Solid Phase Microextraction–Gas Chromatography

Dedi Hanwar, Tiara Nur Arsanti, Riesta Primaharinastiti, Mochammad Yuwono
Co-Amoxiclav tablets are coated tablets. The tablet coating process requires an organic solvent in the sealing stage. Several processes are carried out to remove organic solvents in the finished drug product, such as heating and pressure reduction, which still leaves organic solvents in the finished...
Proceedings Article

Study of Surface Plasmon Resonance of Gold Nanoparticles Stabilized by L-arginine

Amaria Amaria, Dina Kartika Maharani, Maria Monica Sianita
Gold nanoparticles (AuNP) capped by L-arginine have been synthesized. In this research, gold nanoparticles were synthesized by reducing the solution of Au(III) to Au(0) using trisodium citrate and capping agent L-arginine as a stabilizer. The ratio of Au(III) ions to amino acids is optimized to obtain...
Proceedings Article

Campesterol compound from Methanol Fraction of Brotowali (Tinospora crispa) Stem Bark

Weny A. J Musa, Suleman Duengo, Ahmad Kadir Kilo
Tinospora crispa is a plant of the Menispermaceae family which is one of the endemic plants in Indonesia, commonly called as Brotowali. Tinospora crispa have been used traditionally to treat fever, diabetes, rheumatism and sinusitis. The chemical components of the plant have not been reported so far....
Proceedings Article

Study of Pharmacological Activities and Chemical Content of Rambutan (Nephelium Lappaceum L.) Fruit Peel Extract: A Systematic Review

Anggun Mahirotun Nur Sholikhah, Muhtadi
Indonesia has various types of plants that are efficacious as medicine. One of them is rambutan whose peel has medicinal properties. However, rambutan peel has not been widely used by most people. In recent years, there have been many studies that have tested the effectiveness of rambutan peel on health....
Proceedings Article

The Use of Celery (Apium Graveolens L.) for Reducing Blood Pressure in Individual with Hypertension in Indonesia: A Review Paper

Rizki Oktarina, Setyaningrum Rahmawaty
Celery (Apium graveolens L.) contains active compounds that can help lowering blood pressure. The purpose of this study was to present an overview of the effectiveness of celery administration in reducing blood pressure of people with hypertention based on studies performed in Indonesia. Two digital...
Proceedings Article

Systematic Review: Anticancer Potential of Active Compounds from Galangal (Alpinia galanga)

Anugerah Suciati, Maryati
Galangal (Alpinia galanga) is a plant that is widely spread in Southeast Asia and is widely used for cooking spices. Research related to the effect of A. galanga on cancer cells has been carried out. The purpose of this systematic review is to examine the potential of A. galanga as an anticancer agent...
Proceedings Article

Pharmacological Activity of Mangrove Plant Bioactive Compounds Against Cancer Cell Changes: A Systematic Review

Dwi Bagus Pambudi, Haryoto
Cancer is a condition when the body's cells begin to grow abnormally and uncontrollably. Cancer therapy which is often used in medicine is non-selective, it can affect other normal cells that have a toxic effect in addition beside the activity as anticancer, to overcome this herbal plants have potential...
Proceedings Article

Optimization of Peptone Production from Soybeans

Rochmaningsih, Kun Harismah, Akida Mulyaningtyas
Soybeans are the most popular source of vegetable protein for the people of Indonesia, having protein content ranging from 35%–38%. In the protein analysis of 100 mesh size soybean powder using the Kjeldahl method with the Kjeltec 2100 Distilling Unit, the protein content is 35.95. The high protein content...
Proceedings Article

Making Bacillus cereus Bacterial Growth Media from Soybeans (Glycine max (L.) Merril)

Atmojo Sandi Utomo, Kun Harismah, Akida Mulyaningtyas
This study develops a selective medium for the growth of Bacillus cereus from soybeans, which can be directly applied in the laboratory to replace media made from meat extract. This study considers the economic aspect by making inexpensive microbiological media, as well as testing the halal aspect so...
Proceedings Article

Review: Diphenylphosphane Derivatives of Ketoconazole and Oteseconazole/VT-1161, Promising New Azole Compounds in the Treatment of Candida albicans Infections

Muhammad Rosyid As Sabiq, Peni Indrayudha
In some treatments of diseases, there is a risk of possible fungal infection of Candida albicans. The risk of infection can be exacerbated by the occurrence of resistance to anti-fungal drugs, including resistance to azole compounds. The purpose of this research is to conduct a review of new azole compounds...
Proceedings Article

Cytotoxicity of Soursop (Annona Muricata L.) Seed Protein on HeLa and Vero Cells

Diana Shofita Sari, Peni Indrayudha, Maryati, Azis Saifudin, Cita Hanif Muflihah
Cervical cancer was the fourth-highest incidence of female cancer globally in 2020 and the second-highest incidence of female cancer in Indonesia in 2019. Chemotherapy frequently causes side effects and resistance; thus, cancer therapeutic agents must be developed to find selective anticancer drugs....
Proceedings Article

Cytoxicity of Melinjo (Gnetum Gnemon L.) Seed Protein on MCF-7 and Vero Cells and Its Antiproliferation Activity

Sonia Tithaning Sukma, Peni Indrayudha, Maryati, Azis Saifudin, Cita Hanif Muflihah
Melinjo seeds are one of the plants that have the potential to be developed as anticancer drugs. This study aimed to determine the cytotoxic activity of melinjo seed protein against MCF-7 and vero cells, and to determine the antiproliferative activity of melinjo seed protein against MCF-7 cells. The...
Proceedings Article

Cytotoxic Activity and Antiproliferation of Soursop Seed (Annona muricata L.) Protein on MCF-7 Cells

Itsna Sofia Rahma, Peni Indrayudha, Maryati, Azis Saifudin, Cita Hanif Muflihah
One of the new anticancer treatments that can be developed is a protein similar to RIPs. RIP is an enzyme found in various parts of plants that is toxic and can inhibit protein synthesis. Soursop seeds (Annona muricata L.) may be developed into anticancer. The plant of the same genus, Annona Squamosa...
Proceedings Article

Cytotoxic Activity and Antiproliferation of Soursop Seed Protein (Annona muricata) Against 4T1 Cells

Monarita Puspita Dewi, Peni Indrayudha, Maryati, Azis Saifudin, Cita Hanif Muflihah
Current cancer treatments still have a lot of negative impacts, so it is necessary to find alternative treatments that come from nature or plants that have anti-cancer activity. Plants that have the potential to be anti-cancer agents are plants that contain Ribosome-Inactivating Proteins (RIPs). Soursop...
Proceedings Article

Cytotoxic Activity of Melinjo Seed Protein (Gnetum Gnemon L.) Against 4T1 Cells and Hela Cells, and Antiproliferation Test on 4T1 Cells

Kurnia Indah Fatmawati, Peni Indrayudha, Maryati, Azis Saifudin, Cita Hanif Muflihah
Melinjo (Gnetum gnemon L.) is an easily discovered plant in Indonesia. The previous researchers documented that the Melinjo seed has anticancer activity. This plant contains a high concentration of Ribosome Inactive Proteins (RIPs), which could inhibit protein synthesis. The research aims to determine...
Proceedings Article

In silico Analysis for Discovery of Dengue Virus Inhibitor from Natural Compounds

Miah Roney, Md. Sanower Hossain, Mohd Fadhlizil Fasihi Mohd Aluwi
Dengue fever is a growing global health problem, with millions of virus illnesses occurring each year. Unfortunately, there is no approved treatment available. DENV NS5 RdRp protease produced by the dengue virus (DENV) is being investigated as a promising therapeutic target for developing efficient dengue...
Proceedings Article

Exploring the Genetic Differences Between Small Cell and Non-small Cell Lung Cancer Using Bioinformatic Approaches: A Preliminary Study

Muhammad Amru Nazri, Faris Aizat Ahmad Fajri, Muhamad Harith Zulkifli, Fazlin Mohd Fauzi
Lung cancer can be categorized into two types, which are Non Small Cell Lung Carcinoma (NSCLC) and Small Cell Lung Carcinoma (SCLC). 85% of lung cancer cases are NSCLC, although SCLC is the more aggressive. Mutation of EGFR, ALK and KRAS are characteristics of NSCLC and these findings have led to the...