Artery Research

Volume 5, Issue 4, December 2011, Pages 143 - 143

5.4 LIFETIME ADHERENCE TO A MEDITERRANEAN DIET (MD) PATTERN IS ASSOCIATED WITH LOWER CAROTID STIFFNESS IN YOUNG ADULTS: THE AMSTERDAM GROWTH AND HEALTH LONGITUDINAL STUDY

Authors
R.J.J.M. van de Laar1, C.D.A. Stehouwer1, B.C.T. van Bussel1, M.H. Prins1, J.W.R. Twisk2, I. Ferreira1
1Maastricht University Medical Centre, Maastricht, Netherlands
2VU University Medical Center, Amsterdam, Netherlands
Available Online 29 November 2011.
DOI
10.1016/j.artres.2011.10.222How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Purpose: To investigate whether lifetime adherence to an MD pattern (i.e., from adolescence to adulthood) is associated with arterial stiffness in adults.

Methods: Longitudinal data on dietary intake (2–8 repeated measures; ages 13–36) were retrieved for 373 subjects in whom carotid stiffness was assessed by means of ultrasonography at age 36. An MDscore [range: 0 to 9 (higher values indicate better adherence)] was calculated based on values < or > the sex-specific medians or pre-defined cut-off values of vegetables, legumes, fruits/nuts, whole grains, fish, meat/poultry, dairy products, alcohol and the ratio of mono-unsaturated to saturated lipids intake. Adherence to an MD pattern (yes/no) was defined based on values > or < median of the MDscore. We used generalized estimating equations to compare, throughout the 24-yr longitudinal period, the MDscore between subjects with increasing levels [i.e., tertiles (T)] of the inversed distensiblity (DC−1) and compliance coefficients, and Young’s elastic modulus.

Results: After adjustment for height, energy intake, physical activity, smoking and mean arterial pressure, and as compared to subjects with ‘stiffer’ arteries (i.e., in T3), those with ‘less stiff’ arteries (T1) had a higher lifetime mean MDscore [e.g., +0.44 (95%CI: 0.20–0.69), when considering the DC−1 levels - Figure]. Subjects with ‘less stiff’ arteries were also more likely to have had adhered to an MD pattern throughout the longitudinal period than those with ‘stiffer’ arteries [OR=1.68 (1.22–2.31)].

Discussion: Promoting adherence to the MD throughout the course of young life might offer an important means to prevent accelerated arterial stiffening later in life.

Journal
Artery Research
Volume-Issue
5 - 4
Pages
143 - 143
Publication Date
2011/11/29
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2011.10.222How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - R.J.J.M. van de Laar
AU  - C.D.A. Stehouwer
AU  - B.C.T. van Bussel
AU  - M.H. Prins
AU  - J.W.R. Twisk
AU  - I. Ferreira
PY  - 2011
DA  - 2011/11/29
TI  - 5.4 LIFETIME ADHERENCE TO A MEDITERRANEAN DIET (MD) PATTERN IS ASSOCIATED WITH LOWER CAROTID STIFFNESS IN YOUNG ADULTS: THE AMSTERDAM GROWTH AND HEALTH LONGITUDINAL STUDY
JO  - Artery Research
SP  - 143
EP  - 143
VL  - 5
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2011.10.222
DO  - 10.1016/j.artres.2011.10.222
ID  - vandeLaar2011
ER  -