Artery Research

Volume 5, Issue 4, December 2011, Pages 161 - 161

P4.08 BIOMECHANICAL STUDY OF ANEURYSM RUPTURE

Authors
J. Kim1, A. Romo1, P. Badel1, A. Duprey2, J.N. Albertini2, J.P. Favre2, S. Avril1
1Ecole Nationale Supérieure des Mines de Saint-Etienne, Center for Health Engineering, CNRS UMR5146, INSERM IFRESIS, Saint Etienne, France
2CHU Nord University Hospital Center, Department of Vascular Surgery, Saint Etienne, France
Available Online 29 November 2011.
DOI
10.1016/j.artres.2011.10.053How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

The rupture of aortic aneurysms is a catastrophic event that represents a major public health issue. It has received a large interest from the scientific community. However, only limited research has provided quantitative values of mechanical stresses that may assess the risks of rupture of aneurysms [1].

In this study we have applied an imaging approach for measuring the deformations of the aneurysmal tissue tested in a biaxial inflation test [2]. The tissues have been taken from the thoracic ascending aorta of 6 diseased patients operated for aneurysm treatment by conventional surgery at the University Hospital of Saint-Etienne, France.

Quantitative values of ultimate stresses are reported in Tab. 1. Rupture is anisotropic, but primarily induced by axial stresses. Moreover, it is observed that rupture in aneurysms is preceded by a local weakening of the mechanical properties of the tissue, especially in the intima and media layers which are more fragile, and that these effects announcing a pending rupture can be detected by advanced imaging techniques. Our investigations continue in that sense for proposing novel diagnosis methodologies based on these observations.

Patient gender M M M M M M
Age 81 81 68 69 76 76
Type adventitia media media media media adventitia
Stress at rupture (MPa) 0.6257 0.3719 0.3686 0.4107 0.3483 1.0522
Tab. 1.

Quantitative values of ultimate stress measured at rupture

Refs

[1]ZY Li, U Sadat, J U-King-Im, TY Tang, DJ Bowden, PD Hayes, and JH Gillard, Association between aneurysm shoulder stress and abdominal aortic aneurysm expansion - a longitudinal follow-up study, Circulation, Vol. 122, No. 18, 2010, pp. 1815-22.
[2]J Kim, S Avril, P Badel, A Duprey, and JP Favre, Characterization of failure in human aortic tissue using digital image correlation, Computer Methods in Biomechanics and Biomedical Engineering, 2011. in press
Journal
Artery Research
Volume-Issue
5 - 4
Pages
161 - 161
Publication Date
2011/11/29
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2011.10.053How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - J. Kim
AU  - A. Romo
AU  - P. Badel
AU  - A. Duprey
AU  - J.N. Albertini
AU  - J.P. Favre
AU  - S. Avril
PY  - 2011
DA  - 2011/11/29
TI  - P4.08 BIOMECHANICAL STUDY OF ANEURYSM RUPTURE
JO  - Artery Research
SP  - 161
EP  - 161
VL  - 5
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2011.10.053
DO  - 10.1016/j.artres.2011.10.053
ID  - Kim2011
ER  -