P6.16 DETERMINATION OF CAROTID AND FEMORAL WAVE SPEED AND DISTENSIBILITY IN A HEALTHY POPULATION USING A NEW NON-INVASIVE TECHNIQUE

A. Borlotti; S. Vermeersch; E. Rietzschel; P. Segers; A.W. Khir

doi:10.1016/j.artres.2011.10.101

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Volume 5, Issue 4, December 2011, Pages 176 - 176

P6.16 DETERMINATION OF CAROTID AND FEMORAL WAVE SPEED AND DISTENSIBILITY IN A HEALTHY POPULATION USING A NEW NON-INVASIVE TECHNIQUE

Authors

A. Borlotti¹, S. Vermeersch², E. Rietzschel³, P. Segers², A.W. Khir¹

¹Brunel University, Brunel Institute for Bioengineering, Uxbridge, London, United Kingdom

²Ghent University, IBiTech-bioMMeda, Gent, Belgium

³Ghent University Hospital, Gent, Belgium Local wave speed (c) is a predictor of cardiovascular diseases because is related to arterial distensibility

Available Online 29 November 2011.

DOI: 10.1016/j.artres.2011.10.101 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

In this work, carotid and femoral distensibility were assessed in the Asklepios study population. Local wave speed was determined with a new non-invasive technique based on velocity (U) and diameter (D) measurements (lnDU-loop) [1]. Distensibility was calculated using c and the Bramwell-Hill equation, and changes were studied with respect to age and gender.

Figure 1 shows changes in carotid and femoral wave speed (a) and distensibility (b) with age and gender. Carotid wave speed increases and distensibility decreases with age (a part from male aged 40–45 and 45–50) and there is no difference between males and females. In the femoral artery, these parameters do not change with age and wave speed is lower and distensibility is higher in females.

The mechanical properties of elastic (carotid) and muscular (femoral) arteries change differently with age, which is in line with results of other investigators. The new technique provides a means for the determination of arterial distensibility using non-invasive measurements of D and U, which can potentially be clinically useful as they could be taken using Doppler ultrasound.

1.Feng and Khir, Determination of wave speed and wave separation in the arteries using diameter and velocity, J.Biomech, Vol. 43, No. 3, 2010, pp. 455-462.

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Journal: Artery Research
Volume-Issue: 5 - 4
Pages: 176 - 176
Publication Date: 2011/11/29
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2011.10.101 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - A. Borlotti
AU  - S. Vermeersch
AU  - E. Rietzschel
AU  - P. Segers
AU  - A.W. Khir
PY  - 2011
DA  - 2011/11/29
TI  - P6.16 DETERMINATION OF CAROTID AND FEMORAL WAVE SPEED AND DISTENSIBILITY IN A HEALTHY POPULATION USING A NEW NON-INVASIVE TECHNIQUE
JO  - Artery Research
SP  - 176
EP  - 176
VL  - 5
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2011.10.101
DO  - 10.1016/j.artres.2011.10.101
ID  - Borlotti2011
ER  -

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