Artery Research

Volume 4, Issue 4, December 2010, Pages 159 - 159

P3.01 WHY THE RETURN TIME OF THE REFLECTED WAVE CHANGES LITTLE WITH AGE

Authors
B.E. Westerhof1, N. Westerhof2
1BMEYE, Amsterdam, Netherlands
2VU University Medical Center, Amsterdam, Netherlands
Available Online 2 December 2010.
DOI
10.1016/j.artres.2010.10.044How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Introduction: The return time of the reflected wave as a function of age has been reported to decrease by some but unaltered by others (1). The increased pulse wave velocity (c) suggests earlier return with age, but the effect of reflection (2) and foot-foot velocity (cf-f) of the backward wave are not accounted for.

Method: We consider the aorta to be a uniform tube (phase velocity, c), with at its distal end the impedance of lower body and legs. With age the aortic wall stiffens and c increases. We assume, for simplicity, the distal bed not to change.

Results: With stiffer aorta, cf-f of the forward wave (∼c) is increased. However, the phase angle of the reflection coefficient becomes more negative, i.e., the apparent aortic length increases. The reflected wave contains few high harmonics, and its foot pertains to low frequencies traveling with a high cf-f=capp (we found capp≈2.5c), this high speed contributes little to the return time. Thus, the stiffer aorta increases forward wave speed which shortens the return time, while the phase angle of reflection lengthens the return time (2). The two opposite effects are comparable in magnitude, and therefore the return time is quite independent of age.

Conclusion: With age, the forward wave travels faster (increased cf-f), but the increased phase of the reflection coefficient counteracts this and therefore the return time changes little with age.

1.AJ Baksi et al., J Am Coll Cardiol, Vol. 54, 2009, pp. 2087-92.
2.BE Westerhof et al., Hypertension, Vol. 52, 2008, pp. 478-83.
Journal
Artery Research
Volume-Issue
4 - 4
Pages
159 - 159
Publication Date
2010/12/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2010.10.044How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - B.E. Westerhof
AU  - N. Westerhof
PY  - 2010
DA  - 2010/12/02
TI  - P3.01 WHY THE RETURN TIME OF THE REFLECTED WAVE CHANGES LITTLE WITH AGE
JO  - Artery Research
SP  - 159
EP  - 159
VL  - 4
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.10.044
DO  - 10.1016/j.artres.2010.10.044
ID  - Westerhof2010
ER  -