P1.04 PREDICTORS OF VASCULAR AGE IN A POPULATION WITH CARDIOVASCULAR RISK FACTORS

M. Loboz-Rudnicka; J. Jaroch; Z. Bociaga; E. Kruszynska; B. Ciecierzynska; M. Dziuba; K. Dudek; I. Uchmanowicz; K. Loboz-Grudzien

doi:10.1016/j.artres.2012.09.041

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Volume 6, Issue 4, December 2012, Pages 152 - 152

P1.04 PREDICTORS OF VASCULAR AGE IN A POPULATION WITH CARDIOVASCULAR RISK FACTORS

Authors

M. Loboz-Rudnicka¹, J. Jaroch¹, Z. Bociaga¹, E. Kruszynska¹, B. Ciecierzynska¹, M. Dziuba¹, K. Dudek³, I. Uchmanowicz², K. Loboz-Grudzien¹^{, 2}

¹T.Marciniak Hospital, Department of Cardiology, Wroclaw, Poland

²Medical University of Wroclaw, Department of Health Science, Wroclaw, Poland

³Wroclaw University of Technology, Wroclaw, Poland

Available Online 17 November 2012.

DOI: 10.1016/j.artres.2012.09.041 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Background: We aimed at evaluating determinants of the vascular age.

Material and Methods: 187 subjects [86 M and 101 W)] with CV risk factors were classified into three categories of the Framingham CV Risk (FR). Their mean carotid intima media thickness (CIMT) and arterial stiffness (a.s.) parameters were assessed. The VA was calculated from the CIMT according to the nomograms from the ARIC Study. The subjects were divided into two groups: 1- VA exceeds the chronological age (CA) for at least 5 years and 2 – others.

Results: The VA > the CA in M and W (M: 68.5 y vs 52.4 y, p < 0.001; W: 67.1 vs 55.00, p<0.001). No relationship between the FR category and classification to group 1 or 2 was observed. In both sexes diabetes mellitus (DM) (M: OR 3.10, 95% CI 1.28 ÷ 7.50, p<0.05; W: OR 4.40, 95%CI 1.85 ÷ 10.47, p=0.001) and additionally in W BMI >25 kg/m2 (OR 5.87, 95%CI 2.15 ÷ 15.99, p=0.009) differentiated group 1 from group 2. Increased β (9.36 vs 7.77, p=0.005) and Ep (131.9 vs 110.1, p< 0.05) in M and Ep (132.3 vs 106.5, p<0.05) in W distinguished group 1 from group 2. In the multivariate analysis, DM and elevated BMI in W and DM and increased β in M were proved to be independent predictors of VA > CA.

Conclusions: FR categories did not allow for prediction if the VA > CA. DM appeared as the strongest predictor of the VA > CA.

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Journal: Artery Research
Volume-Issue: 6 - 4
Pages: 152 - 152
Publication Date: 2012/11/17
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2012.09.041 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - M. Loboz-Rudnicka
AU  - J. Jaroch
AU  - Z. Bociaga
AU  - E. Kruszynska
AU  - B. Ciecierzynska
AU  - M. Dziuba
AU  - K. Dudek
AU  - I. Uchmanowicz
AU  - K. Loboz-Grudzien
PY  - 2012
DA  - 2012/11/17
TI  - P1.04 PREDICTORS OF VASCULAR AGE IN A POPULATION WITH CARDIOVASCULAR RISK FACTORS
JO  - Artery Research
SP  - 152
EP  - 152
VL  - 6
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.09.041
DO  - 10.1016/j.artres.2012.09.041
ID  - Loboz-Rudnicka2012
ER  -

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