Artery Research

Volume 6, Issue 4, December 2012, Pages 177 - 177

P3.02 DESCRIBING WAVES IN THE PULMONARY VEINS: APPLICATION OF A RESERVOIR-WAVE MODEL

Authors
J.C. Bouwmeester, N.G. Shrive, J.V. Tyberg
University of Calgary, Calgary, Canada
Available Online 17 November 2012.
DOI
10.1016/j.artres.2012.09.129How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Background: The pulmonary venous pressure waveform is typically described by the downstream events in the left atrium and ventricle. These downstream events create waves that contribute to the overall waveform.

Methods: In anesthetised open-chest dogs, measurements of pressure and flow were made in the pulmonary artery and vein. Experiments involved increases to blood volume and the application of 10 cm H2O positive end-expiratory pressure (PEEP). The reservoir-wave model describes the reservoir pressure, which is subtracted from measured pressure, to result in the excess pressure (Pexcess). Excess velocity (Uexcess) is similarly formulated. Pexcess and Uexcess are used in wave intensity analysis to calculate wave speed and separate the contributions of waves originating upstream (forward waves) and downstream (backward waves).

Results: Separated waves are shown in the bottom panel of Figure 1. The effect of PEEP resulted in larger decreases to Pbackward (p < 0.001) after the mitral valve opened. As a result, y was lower than x by ∼2.0 mmHg. With PEEP, the delay between arterial and venous forward waves increased from 155 ± 4 ms to 183 ± 4 ms (mean ± SE, p < 0.001).

Figure 1

Common venous markers related to measured pressures (top panel) and the separation of Pexcess into forward and backward components (bottom panel) at control conditions.

Conclusion: The majority of pulmonary venous pressure landmarks can be attributed to the actions of the left atrium and ventricle but the v wave has substantial contributions from waves originating in the pulmonary artery. Diastolic suction has a larger effect with PEEP, presumably from some external constraint applied to the heart and consequently lowered end-systolic left ventricular volume.

Journal
Artery Research
Volume-Issue
6 - 4
Pages
177 - 177
Publication Date
2012/11/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2012.09.129How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - J.C. Bouwmeester
AU  - N.G. Shrive
AU  - J.V. Tyberg
PY  - 2012
DA  - 2012/11/17
TI  - P3.02 DESCRIBING WAVES IN THE PULMONARY VEINS: APPLICATION OF A RESERVOIR-WAVE MODEL
JO  - Artery Research
SP  - 177
EP  - 177
VL  - 6
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.09.129
DO  - 10.1016/j.artres.2012.09.129
ID  - Bouwmeester2012
ER  -