LAA1 HEMODYNAMIC AND STRUCTURAL ARTERIAL PARAMETERS’ ASSOCIATION WITH INTERINDIVIDUAL VARIATIONS OF BODY MASS INDEX IN CHILDHOOD AND ADOLESCENCE

Victoria Garcia; Santiago Curcio; Agustina Zinoveev; Gustavo Giachetto; Pedro Chiesa; Daniel Bia; Yanina Zócalo

doi:10.1016/j.artres.2017.10.022

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Volume 20, Issue C, December 2017, Pages 49 - 50

LAA1 HEMODYNAMIC AND STRUCTURAL ARTERIAL PARAMETERS’ ASSOCIATION WITH INTERINDIVIDUAL VARIATIONS OF BODY MASS INDEX IN CHILDHOOD AND ADOLESCENCE

Authors

Victoria Garcia¹, Santiago Curcio¹, Agustina Zinoveev¹, Gustavo Giachetto², Pedro Chiesa³, Daniel Bia¹, Yanina Zócalo¹

¹Physiology Department, School of Medicine, Centro Universitario de Investigación, Innovación y Diagnóstico Arterial (CUiiDARTE), Uruguay

²Clínica Pediátrica “C”, Centro Hospitalario Pereira Rossell, ASSE, Uruguay

³Pediatric Cardiology Center, Centro Hospitalario Pereira Rossell, Uruguay

Available Online 6 December 2017.

DOI: 10.1016/j.artres.2017.10.022 How to use a DOI?
Abstract: Background: Several works analyze arterial parameters’ (stiffness levels, wall thickness, etc.) association with variations of body mass index (BMI) in pediatric populations.

However, none integrate different arterial parameters as comparable continuous (standardized) variables, in order to assess their association with standardized (age- and sex-independent) BMI scores (zBMI).

Aims: To analyze the association of standardized arterial parameters with interindividual variations of zBMI.

Methods: 609 children and adolescents (mean age/range: 12/4–18 years, 45% females) were studied. Body mass index (BMI) was calculated. zBMI scores were derived from population-based tables. Non-invasive arterial assessment was performed: oscillometric measurements of peripheral systolic (pSBP), diastolic (pDBP) and pulse pressure (pPP), and central (applanation tonometry) systolic (cSBP), diastolic (cDBP) and pulse pressure (cPP); ultrasonographic measurements of common carotid (CCA), femoral (CFA) and brachial (BA) diastolic diameters (DD), and CCA intima-media thickness (cIMT). Arterial elastic moduli (EM) were calculated. Arterial parameters were standardized with equations derived from a reference population (no cardiovascular risk factor exposure). Simple linear regression models were obtained for the different standardized arterial parameters with zBMI as the independent variable. Statistical threshold was 0.05.

Results: We found a positive and significant association between zBMI and standardized pSBP (β = 0.210), pPP (β = 0.150), cSBP (β = 0.204) and cPP (β = 0.188), CCA DD (β = 0.145), FCA (β = 0.143), BA (β = 0.210), cIMT (β = 0.135), and CCA EM (β = 0.117).

Conclusions: Higher zBMI associated higher standardized arterial blood pressure, stiffness levels, diameters and thickness. Hemodynamic parameters presented the stronger associations with zBMI variations.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 20 - C
Pages: 49 - 50
Publication Date: 2017/12/06
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2017.10.022 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Victoria Garcia
AU  - Santiago Curcio
AU  - Agustina Zinoveev
AU  - Gustavo Giachetto
AU  - Pedro Chiesa
AU  - Daniel Bia
AU  - Yanina Zócalo
PY  - 2017
DA  - 2017/12/06
TI  - LAA1 HEMODYNAMIC AND STRUCTURAL ARTERIAL PARAMETERS’ ASSOCIATION WITH INTERINDIVIDUAL VARIATIONS OF BODY MASS INDEX IN CHILDHOOD AND ADOLESCENCE
JO  - Artery Research
SP  - 49
EP  - 50
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.022
DO  - 10.1016/j.artres.2017.10.022
ID  - Garcia2017
ER  -

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