Artery Research

Volume 20, Issue C, December 2017, Pages 94 - 94

P137 NUMERICAL ASSESSMENT AND COMPARISON OF PULSE WAVE VELOCITY METHODS PRESUMING TO MEASURE AORTIC STIFFNESS

Authors
Hasan Obeid1, Gilles Soulat2, Elie Mousseaux2, Stephane Laurent2, Nikolaos Stergiopulos3, Pierre Boutouyrie2, Patrick Segers1
1IBiTech-bioMMeda, ELIS Department, iMinds Medical IT, Ghent University, Ghent, Belgium
2Hôpital Européen Georges-Pompidou, Inserm U970, Paris, France
3Laboratory of Hemodynamics and Cardiovascular Technology, Ecole Polytechnique Fédérale de Lausanne EPFL, Switzerland
Available Online 6 December 2017.
DOI
10.1016/j.artres.2017.10.149How to use a DOI?
Abstract

Recently several methods have been proposed as tools to measure aortic pulse wave velocity (aPWV). The carotid-femoral pulse wave velocity (cf-PWV), the current clinical gold standard method for the noninvasive assessment of aPWV, uses the carotid–femoral pulse transit time (cf-PTT) to derive cf-PWV. The heart-ankle PWV (ha-PWV), brachial-ankle PWV (ba-PWV) and finger-toe (ft-PWV) are also methods presuming to approximate aPWV based on time delays between physiological signals at two locations (∼heart-ankle PTT, ha-PTT; ∼brachial-ankle PTT, ba-PTT; ∼finger-toe PTT, ft-PTT). To test the validity of these methods, we used a 1D arterial network model (143 segments) including the foot and hand circulation.

The arterial tree dimensions and properties were taken from the literature and completed with CT-scans data. We calculated PTT’s with all the methods above.

The calculated PTT’s were compared with the aortic PTT (aPTT), considered as the absolute reference method in this study. The correlation between methods and aPTT was good and significant, cf-PTT (R2 = 0.97; P < 0.001; mean difference 5±2 ms), ha- PTT (R2 = 0.96; P < 0.001; 150±23 ms), ba-PTT (R2 = 0.96; P < 0.001; 70±13 ms) and ft-PTT (R2 = 0.95; P < 0.001; 14±10 ms).

Consequently, good correlation was also observed for the PWV values derived with the tested methods, but absolute values differed because of different path lengths used. In conclusion, our computer model based analyses demonstrate that for PWV methods based on peripheral signals, PTT’s closely correlate with the aPTT, supporting the use of these methods in clinical practice.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
20 - C
Pages
94 - 94
Publication Date
2017/12/06
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2017.10.149How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Hasan Obeid
AU  - Gilles Soulat
AU  - Elie Mousseaux
AU  - Stephane Laurent
AU  - Nikolaos Stergiopulos
AU  - Pierre Boutouyrie
AU  - Patrick Segers
PY  - 2017
DA  - 2017/12/06
TI  - P137 NUMERICAL ASSESSMENT AND COMPARISON OF PULSE WAVE VELOCITY METHODS PRESUMING TO MEASURE AORTIC STIFFNESS
JO  - Artery Research
SP  - 94
EP  - 94
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.149
DO  - 10.1016/j.artres.2017.10.149
ID  - Obeid2017
ER  -