P160 VASCULAR ABNORMALITIES AND HAEMODYNAMIC PATTERN IN OBESE YOUNG ADULTS

Pedro Forcada; Jorge Chiabaut Svane; Sergio Gonzalez; Carol Kotliar; Sebastian Obregon; Carlos Castellaro

doi:10.1016/j.artres.2017.10.181

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Volume 20, Issue C, December 2017, Pages 105 - 105

P160 VASCULAR ABNORMALITIES AND HAEMODYNAMIC PATTERN IN OBESE YOUNG ADULTS

Authors

Pedro Forcada¹, Jorge Chiabaut Svane², Sergio Gonzalez³, Carol Kotliar⁴, Sebastian Obregon⁴, Carlos Castellaro⁵

¹Cemic and Dim Prevencion Cardiovascular, Buenos Aires, Argentina

²Hospital Austral, Buenos Aires, Argentina

³Hospital Austral and Hospital Churruca, Buenos Aires, Argentina

⁴Hospital Austral and Santa Maria De La Salud, Buenos Aires, Argentina

⁵Hospital Austral and Cemic, Buenos Aires, Argentina

Available Online 6 December 2017.

DOI: 10.1016/j.artres.2017.10.181 How to use a DOI?
Abstract: Background: Obesity is linked to a higher prevalence of risk factors, metabolic and inflammatory pathways conducting to increased vascular disease and CV risk.

Objective: To assess vascular disarrangements and haemodynamic patterns in obese young subjects (O) compared with matched lean (L) controls, using non invasive methods.

Methods: From the database of our Non Invasive Vascular Lab with 3964 first evaluated patients, we performed a case control study with 363 sujects, 268 obese and 95 lean, age and sex matched controls. We measured IMT, Plaque analysis, PWV, Endothelial Function (EF) and arterial stiffness (CAP and Aix) (AS) using an oscillometric device (Arteriograph, Tensiomed. Hungary®) and non invasive haemodynamic evaluation using impedance cardiography (Z Logic Exxer®).

Results: Age (O 42.5 + 5; L 43.5 + 11) and sex % (O 80.6%; L 78%) were matched. BMI (O 33.5 + 3.3 L 25 + 1.1Kg/m²), waist (O110.4 + 7.5; L 91.2 + 6.1cm) and BP (SBP O 139.8 + 16.8; L119 + 8.8 and DBP O 89 + 3.9; L 74.3 + 8 mmHg) were higher in O (p < 0.001).CV Risk Factors in O: HTN 68% DLP 59.7% SMKG 24.2% DBT2 7.8% SED 72.4%.The % of abnormalities in IMT (O/L : 65.8/25.3%), Plaques (75.6/38.9%), EF (57.5/33.7%) and PWV (41.4/17.9%) were higher in O (p < 0.001). Central and Peripheral PP were higher in O but not Aix. CI was significantly lower and PVRI and Thoracic Fluid content higher in O.

Conclusion: Young obese patients present a higher prevalence of vascular disarrangements either structural and functional and a haemodynamic pattern of high peripheral resistance with volume expansion that may explain the role of this condition as a CV risk factor.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 20 - C
Pages: 105 - 105
Publication Date: 2017/12/06
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2017.10.181 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Pedro Forcada
AU  - Jorge Chiabaut Svane
AU  - Sergio Gonzalez
AU  - Carol Kotliar
AU  - Sebastian Obregon
AU  - Carlos Castellaro
PY  - 2017
DA  - 2017/12/06
TI  - P160 VASCULAR ABNORMALITIES AND HAEMODYNAMIC PATTERN IN OBESE YOUNG ADULTS
JO  - Artery Research
SP  - 105
EP  - 105
VL  - 20
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2017.10.181
DO  - 10.1016/j.artres.2017.10.181
ID  - Forcada2017
ER  -

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