Dr. Sulaiman Al Habib Medical Journal

Volume 2, Issue 2, June 2020, Pages 72 - 75

Glucose-6-phosphate Dehydrogenase Deficiency in Patients Attending Tertiary Care Health Setting in Peshawar

Authors
Zair Hassan1, Iftikhar Ali2, Faheemullah Khan3, *, ORCID, Muhammad Shahbaz Khan1
1Department of Cardiology, Lady Reading Hospital, Peshawar, Pakistan
2Pharmacy Unit, Paraplegic Center, Hayatabad, Peshawar, Pakistan
3Department of Diagnostic Radiology, Aga Khan University Hospital, Karachi, Pakistan
*Corresponding author. Email: islamianfellow@hotmail.com
Corresponding Author
Faheemullah Khan
Received 29 February 2020, Accepted 2 June 2020, Available Online 18 June 2020.
DOI
10.2991/dsahmj.k.200613.001How to use a DOI?
Keywords
Deficiency; G6PD; hemolysis; Pathans; red blood cells
Abstract

Glucose-6-phosphate Dehydrogenase (G6PD) deficiency is an X-linked disorder that mainly affects red blood cells resulting in its lysis manifesting as hemolytic anemia. The purpose of this study is to measure the burden of this genetic disorder in patients presenting to a tertiary care health setting of Peshawar, Pakistan, in order to validate previous findings. The retrospective records of 1440 patients were retrieved from the Hospital Management and Information System for the period spanning from January 2017 to December 2018. The data of 1402 patients were included in the final analysis. The mean (standard deviation) age of the patients was 15.02 ± 15.50 (range, 0.50–91.50) years. Of the total, 78.1% were males and 21.9% were females. The frequency of G6PD deficiency recorded was 12.50%. The highest proportion was noted in age groups of <5 years (76; 43.4%) and 20–40 years (37; 21.1%). The frequency of the disorder in males and females was 13.79% and 7.82%, respectively. This study records the high burden of G6PD deficiency in Pathans which is comparable to those reported in the literature. G6PD deficiency is relatively more prevalent in this area. Screening and educational programs for G6PD deficiency are recommended in these high-risk areas irrespective of sex to prevent G6PD deficiency-related morbidity.

Copyright
© 2020 Dr. Sulaiman Al Habib Medical Group. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Dr. Sulaiman Al Habib Medical Journal
Volume-Issue
2 - 2
Pages
72 - 75
Publication Date
2020/06/18
ISSN (Online)
2590-3349
ISSN (Print)
2666-819X
DOI
10.2991/dsahmj.k.200613.001How to use a DOI?
Copyright
© 2020 Dr. Sulaiman Al Habib Medical Group. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Zair Hassan
AU  - Iftikhar Ali
AU  - Faheemullah Khan
AU  - Muhammad Shahbaz Khan
PY  - 2020
DA  - 2020/06/18
TI  - Glucose-6-phosphate Dehydrogenase Deficiency in Patients Attending Tertiary Care Health Setting in Peshawar
JO  - Dr. Sulaiman Al Habib Medical Journal
SP  - 72
EP  - 75
VL  - 2
IS  - 2
SN  - 2590-3349
UR  - https://doi.org/10.2991/dsahmj.k.200613.001
DO  - 10.2991/dsahmj.k.200613.001
ID  - Hassan2020
ER  -