Proceedings of the 1st Aceh International Dental Meeting (AIDEM 2019), Oral Health International Conference On Art, Nature And Material Science Development 2019

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Anti-Biofilm of Various Histatin 5 Concentrations Against Streptococcus Mutans From Salivary Isolate

Authors
Dharli Syafriza, Heriandi Sutadi, Ameta Primasari, Yahwardiyah Siregar
Corresponding Author
Dharli Syafriza
Available Online 1 February 2021.
DOI
10.2991/ahsr.k.210201.005How to use a DOI?
Keywords
biofilm formation, Streptococcus mutans, histatin 5, crystal violet
Abstract

Streptococcus mutan is the main agent infection of dental caries. Histatin 5 has been reported as the antimicrobial agents also to prevent the formation of biofilms of oral pathogen biofilm, like S. mutans involve in dental caries pathogenesis. This study aims to determine the effect of anti-biofilm of histatin 5 on the S. mutans salivary isolate. Identify of S. mutans used to the selective medium (TYS20B) also confirmed by Gram staining and the anti-biofilm S. mutans was assayed by crystal violet 0.1% µl/U. Meanwhile, the value of anti-biofilm analyzed by Enzyme-linked immunosorbent assay (ELISA) reader, based on the optical density in wavelength 575 nm. The potency of the histatin 5 to anti-biofilm of S. mutans salivary isolate among the concentration 25 and 50 ppm higher than the positive control, but in 12.5 and 6.25 ppm are lower than the positive control. Among concentration as the anti-biofilm of S. mutans were significant (p<0.05). Histatin 5 has potential as the anti-biofilm of S. mutans and the concentration of 50 and 25 ppm can be recommended for the simulation of anti-S. mutans.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 1st Aceh International Dental Meeting (AIDEM 2019), Oral Health International Conference On Art, Nature And Material Science Development 2019
Series
Advances in Health Sciences Research
Publication Date
1 February 2021
ISBN
10.2991/ahsr.k.210201.005
ISSN
2468-5739
DOI
10.2991/ahsr.k.210201.005How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Dharli Syafriza
AU  - Heriandi Sutadi
AU  - Ameta Primasari
AU  - Yahwardiyah Siregar
PY  - 2021
DA  - 2021/02/01
TI  - Anti-Biofilm of Various Histatin 5 Concentrations Against Streptococcus Mutans From Salivary Isolate
BT  - Proceedings of the 1st Aceh International Dental Meeting (AIDEM 2019), Oral Health International Conference On Art, Nature And Material Science Development 2019
PB  - Atlantis Press
SP  - 22
EP  - 26
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210201.005
DO  - 10.2991/ahsr.k.210201.005
ID  - Syafriza2021
ER  -