Prognostic Value of Neutrophil-Lymphocyte Ratio, D-Dimer Levels, and Scoring of Lung Lesion on Chest X-Ray on Mortality of COVID-19 Patients

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DOI

10.2991/ahsr.k.210723.032How to use a DOI?

Keywords

prognostic value, neutrophil-lymphocyte ratio, D-dimer, chest X-ray scoring, COVID-19

Abstract

Acute Respiratory Distress Syndrome (ARDS) plays an important role that increases mortality in COVID-19 patients. Several parameters have been tried to predict the patient’s condition for worsening and even death. The objective of this study was to determine the prognostic value of the neutrophil-lymphocyte ratio (NLR), D-Dimer levels, and the degree of severity of lung lesions on chest X-rays on patient mortality. A cross-sectional restrospective study was conducted on 53 patients with positive PCR at Kebon Jati Hospital Bandung for the period September-December 2020. Each patient who was admitted, carried out routine examinations of NLR, D-Dimer, and chest X-ray. There were 40 (75.5%) survival patients and 13 (24.5%) patients died. The mean NLR, D-Dimer, and score of lung lesions on chest X-rays of patients who died were higher than those of the survivor. NLR was 8.59 vs 4.10; P = 0.002, D-Dimer was 3,285.08 vs 1,489.33; P = 0.00 and scoring for lung lesions on chest X-ray was 11.00 vs 6.82; P = 0.001. The predictive ability of these parameters shown by the Area Under Curve (AUC), with the highest predictive value was represented by the AUC NLR of 0.0840, P = 0.000. The cut-off NLR value was 5.07 with a sensitivity of 92.3% and a specificity of 79.5% in predicting the occurrence of death due to COVID-19. The results showed that the NLR, D-Dimer, and thoracic lesion scoring at the time of admission to the hospital have prognostic values for the mortality of COVID-19 patients.

Copyright

© 2021, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Yudith Yunia Kusmala
AU  - Jusron Iriawan
AU  - Fariz Albarri
AU  - Tersia Viradanti
AU  - Sunnatul Mufarrohah
PY  - 2021
DA  - 2021/07/24
TI  - Prognostic Value of Neutrophil-Lymphocyte Ratio, D-Dimer Levels, and Scoring of Lung Lesion on Chest X-Ray on Mortality of COVID-19 Patients
BT  - Proceedings of the 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on "Emergency Preparedness and Disaster Response during COVID 19 Pandemic" (ASMC 2021)
PB  - Atlantis Press
SP  - 128
EP  - 131
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.210723.032
DO  - 10.2991/ahsr.k.210723.032
ID  - Kusmala2021
ER  -