Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022)

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Expression of Immunoglobulin a (IgA) in Wistar Rats Fed and Infected by Salmonella Typhimurium: Immunohistochemical Studies

Authors
Norma Farizah Fahmi1, *, Rizka Efi Mawli1
1STIKes Ngudia Husada Madura, Gebang, Indonesia
*Corresponding author. Email: rezaiei.cha@gmail.com
Corresponding Author
Norma Farizah Fahmi
Available Online 26 June 2023.
DOI
10.2991/978-94-6463-202-6_7How to use a DOI?
Keywords
Immunoglobin A; Salmonella typhi; Probiotics
Abstract

Typhoid fever caused by Salmonella enterica serotype Typhi continues to be a public health problem in developing countries and is a cause of illness and death. The emergence of the problem of antibiotic resistance has also worsened cases of typhoid fever. Probiotic bacteria or lactic acid bacteria (LAB) can be used as an alternative because they provide several benefits for the host, including protection from pathogenic bacteria to increase levels of Immunoglobulin A. This study used LAB species Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus salivarius, Bifidobacterium infantis, Bifidobacterium lactis, Bifidobacterium longum, and Lactococcus lactis found in commercial probiotics. The mixture of isolates was given to white rats (Rattus norvegicus) that had been infected with Salmonella typhi with a dose variation of 0.5 ml, 1 ml, and 2 ml, and the expression of immunoglobulin A (IgA) was observed. The results showed that commercial probiotic isolates could maintain the expression of Immunoglobulin A. in mice infected with Salmonella typhi with the best dose of 2 mL.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022)
Series
Advances in Health Sciences Research
Publication Date
26 June 2023
ISBN
10.2991/978-94-6463-202-6_7
ISSN
2468-5739
DOI
10.2991/978-94-6463-202-6_7How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Norma Farizah Fahmi
AU  - Rizka Efi Mawli
PY  - 2023
DA  - 2023/06/26
TI  - Expression of Immunoglobulin a (IgA) in Wistar Rats Fed and Infected by Salmonella Typhimurium: Immunohistochemical Studies
BT  - Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022)
PB  - Atlantis Press
SP  - 43
EP  - 51
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-202-6_7
DO  - 10.2991/978-94-6463-202-6_7
ID  - Fahmi2023
ER  -