Prenatal ultrasonography screening fetal autosomal trisomy

DOI

10.2991/icmia-16.2016.37How to use a DOI?

Keywords

Amniocentesis; Cordocentesis; Karyotyping ;Ultrasonography; Trisomy.

Abstract

Objective To investigate the value of prenatal ultrasonography screening fetal autosomal trisomy(trisomy 21 trisomy 18 trisomy 13).Methods Amniocentesis and cordocentesis were performed on 6425 pregnant women respectively with indications for prenatal diagnosis to detect karyotype of the fetus during second trimester and late pregnancy, The detection rate of trisomy 21,trisomy 18 ,trisomy 13 was compared in pregnant women of different indications To analyze the relationship between the ultrasonography abnormalities and these trisomy . Results In chromosomal karyotypes analysis of 6425 pregnant women by Amniocentesis and cordocentesis, 98 trisomy (66 trisomy 21, 28 trisomy 18, 4 trisomy 13) were detected, The detection rate of trisomy 1.53%; There were 424 in 6425 pregnant women with ultrasonography abnormalities, 30 trisomy (16 trisomy 21, 12 trisomy 18 , 2 trisomy 13) were found within them and the detection rate of trisomy was 7.08%, the detection rate of trisomy detected by ultrasound (7.08% ) was higher than the 18-trisomy high-risk group (1.42%) , advanced age group(0.88%), the Down,s syndrome high risk group(0.83%) (0.00%) (all P 0.05) ; no significant difference was detected in trisomy detection rate between the abnormal ultrasound group (7.08%) and the NTD high risk group (4.76%) (P 0.05).Conclusions Prenatal ultrasonography is great value in screening fetal autosomal trisomy.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Yu-Ping Pan
PY  - 2016/11
DA  - 2016/11
TI  - Prenatal ultrasonography screening fetal autosomal trisomy
BT  - Proceedings of the 2016 5th International Conference on Measurement, Instrumentation and Automation (ICMIA 2016)
PB  - Atlantis Press
SP  - 200
EP  - 204
SN  - 1951-6851
UR  - https://doi.org/10.2991/icmia-16.2016.37
DO  - 10.2991/icmia-16.2016.37
ID  - Pan2016/11
ER  -