Research of Ofloxacin Based on Terahertz Spectrum
Song Zhang, Xiai Chen, Xiaohong Gu, Qiang Wang, Ling Wang
Available Online January 2017.
- https://doi.org/10.2991/icmmita-16.2016.267How to use a DOI?
- Terahertz time-domain spectroscopy; Absorption spectrum; Density functional theory; Ofloxacin
- The absorption coefficient, refractive index and optical fingerprint characteristics were acquired by terahertz time-domain spectroscopy in the range of 0.4~1.5THz of the capsule drug ofloxacin. The results show that ofloxacin had multiple absorption peaks with different intensities within the frequency range, and the absorption coefficient spectrum could be used for the identification of ofloxacin. In the range of 0.4~1.5THz,the absorption spectra of ofloxacin molecules were simulated by Gaussion software. The vibration modes of some absorption peaks in the absorption spectra were analyzed and identified using the density functional theory. At 1.06 and 1.13THz, the experimental results show that the absorption peaks are consistent with the absorption peaks of 1.07 and 1.18THz in the theoretical spectrum, which are caused by the vibrational modes in the molecule ofloxacin.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Song Zhang AU - Xiai Chen AU - Xiaohong Gu AU - Qiang Wang AU - Ling Wang PY - 2017/01 DA - 2017/01 TI - Research of Ofloxacin Based on Terahertz Spectrum BT - Proceedings of the 2016 4th International Conference on Machinery, Materials and Information Technology Applications PB - Atlantis Press SP - 1146 EP - 1149 SN - 2352-538X UR - https://doi.org/10.2991/icmmita-16.2016.267 DO - https://doi.org/10.2991/icmmita-16.2016.267 ID - Zhang2017/01 ER -