Proceedings of the 3rd International Conference on Biology, Science and Education (IcoBioSE 2021)

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Antiviral Potential of Ethanol Extracts of Andalas Endophytic Bacterial Isolate B. J.T.A 2.1 Fermentation Products

Authors
Dwi Hilda Putri1, *, Azwir Anhar1, Irdawati1, Mades Fidendy1, Nurhasnah2
1Biology Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia
2Sciences-Physics Department, Faculty of Tarbiyah and Education, Universitas Islam Negeri (UIN) Imam Bonjol, Padang, Indonesia
*Corresponding author. Email: dwihildaputri.08@gmail.com
Corresponding Author
Dwi Hilda Putri
Available Online 22 May 2023.
DOI
10.2991/978-94-6463-166-1_41How to use a DOI?
Keywords
Anti Dengue; Endophytic Bacteria; Andalas
Abstract

The most prevalent infectious disease in tropical and subtropical regions is dengue, which is brought on by the dengue virus (DENV) and endemic illnesses. There is currently no antiviral medication specifically for dengue illness. It is understood that viral load and illness severity are correlated. Andalas Endophytic Bacterial Isolate B.J.T.A 2.1 Fermentation products An important active ingredient responsible for the antiviral activity has been found. This research will examine the antiviral effects of Andalas Endophytic Bacterial Isolate B.J.T.A 2.1 Fermentation products ethanol extract on DENV-2 in vitro with its toxicity in cell line. By using a focus assay and an MTT assay, respectively, vero cells were used to test the antiviral activity (IC50) and toxicity (CC50) in vitro. In this investigation, the IC50 acquired value was 17,91 g/mL, while the CC50 acquired value was 85,4 g/mL. The SI value of Andalas Endophytic Bacterial Isolate B.J.T.A 2.1 Fermentation products was 4.8.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 3rd International Conference on Biology, Science and Education (IcoBioSE 2021)
Series
Advances in Biological Sciences Research
Publication Date
22 May 2023
ISBN
10.2991/978-94-6463-166-1_41
ISSN
2468-5747
DOI
10.2991/978-94-6463-166-1_41How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Dwi Hilda Putri
AU  - Azwir Anhar
AU  - Irdawati
AU  - Mades Fidendy
AU  - Nurhasnah
PY  - 2023
DA  - 2023/05/22
TI  - Antiviral Potential of Ethanol Extracts of Andalas Endophytic Bacterial Isolate B. J.T.A 2.1 Fermentation Products
BT  - Proceedings of the 3rd International Conference on Biology, Science and Education (IcoBioSE 2021)
PB  - Atlantis Press
SP  - 310
EP  - 317
SN  - 2468-5747
UR  - https://doi.org/10.2991/978-94-6463-166-1_41
DO  - 10.2991/978-94-6463-166-1_41
ID  - Putri2023
ER  -