Green Synthetic Strategies and Medicinal Applications of Benzofuran: A Review

Amulya Sinha; Arzoo Siddiqui; Vaibhav Tripathi; Amit Yadav; Girish Singh; Nikhat Fatima; Gautam Kumar; Justin Masih; Vivek Bhadauria

doi:10.2991/978-94-6463-876-9_18

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Green Synthetic Strategies and Medicinal Applications of Benzofuran: A Review

Authors

Amulya Sinha¹^{, *}, Arzoo Siddiqui¹, Vaibhav Tripathi¹, Amit Yadav¹, Girish Singh¹, Nikhat Fatima¹, Gautam Kumar¹, Justin Masih¹, Vivek Bhadauria¹

¹Green Laboratory, Department of Chemistry, Ewing Christian College, University of Allahabad, Prayagraj, India, 211003

^*Corresponding author. Email: amulya.sinha28@gmail.com

Corresponding Author

Amulya Sinha

Available Online 23 October 2025.

DOI: 10.2991/978-94-6463-876-9_18 How to use a DOI?
Keywords: benzofuran; heterocycles; antitumor activity; one pot reaction; antiviral activity; anticancer activity
Abstract: Benzofuran derivatives are one of the main groups of biologically relevant heterocycles found in nature. Several benzofurans possess a broad spectrum of therapeutic properties, which implies that this class of chemicals is unambiguously fascinating. Owing to their potent biological attributes along with their applications as pharmacological agents, benzofuran and its analogues have attracted medicinal chemists and pharmacologists. Owing to the extensive array of biological features of benzofurans, medicinal chemists have become intrigued in their structure-activity interactions. Consequently, target molecules in several illness circumstances have been identified. Its significance for medicinal chemistry research is demonstrated by the remarkable production of benzofuran derivatives to treat a broad range of ailments in a relatively short span of time. The current review describes the various synthetic strategies and the pharmacological potential possessed by the Benzofuran nucleus.
Copyright: © 2025 The Author(s)
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title: Proceedings of the International Conference on Sustainable Science and Technology for Tomorrow (SciTech 2024)
Series: Atlantis Advances in Applied Sciences
Publication Date: 23 October 2025
ISBN: 978-94-6463-876-9
ISSN: 3091-4442
DOI: 10.2991/978-94-6463-876-9_18 How to use a DOI?
Open Access: Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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ris enw bib

TY  - CONF
AU  - Amulya Sinha
AU  - Arzoo Siddiqui
AU  - Vaibhav Tripathi
AU  - Amit Yadav
AU  - Girish Singh
AU  - Nikhat Fatima
AU  - Gautam Kumar
AU  - Justin Masih
AU  - Vivek Bhadauria
PY  - 2025
DA  - 2025/10/23
TI  - Green Synthetic Strategies and Medicinal Applications of Benzofuran: A Review
BT  - Proceedings of the International Conference on Sustainable Science and Technology for Tomorrow (SciTech 2024)
PB  - Atlantis Press
SP  - 236
EP  - 254
SN  - 3091-4442
UR  - https://doi.org/10.2991/978-94-6463-876-9_18
DO  - 10.2991/978-94-6463-876-9_18
ID  - Sinha2025
ER  -

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