A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies
- https://doi.org/10.1016/j.artres.2015.11.001How to use a DOI?
- Arterial stiffening; Scanning acoustic microscopy; Cholesterol; Glucose; Blood pressure; Pulse wave velocity; Acoustic wave speed
This study explores the use of scanning acoustic microscopy (SAM) as a potential tool for characterisation of arterial stiffness using aortic biopsies. SAM data is presented for human tissue collected during aortic bypass graft surgery for multi-vessel coronary artery disease. Acoustic wave speed as determined by SAM was compared to clinical data for the patients namely, pulse wave velocity (PWV), blood pressure, cholesterol and glucose levels. There was no obvious trend relating acoustic wave speed to PWV values, and an inverse relationship was found between systolic and diastolic blood pressure and acoustic wave speed. However, in patients with a higher cholesterol or glucose level, the acoustic wave speed increased. A more detailed investigation is needed to relate SAM data to clinical measurements.
- © 2015 The Authors. Published by Elsevier Ltd.
- Open Access
- This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Cite this article
TY - JOUR AU - Riaz Akhtar AU - J. Kennedy Cruickshank AU - Xuegen Zhao AU - Brian Derby AU - Thomas Weber PY - 2015 DA - 2015/12/12 TI - A pilot study of scanning acoustic microscopy as a tool for measuring arterial stiffness in aortic biopsies JO - Artery Research SP - 1 EP - 5 VL - 13 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2015.11.001 DO - https://doi.org/10.1016/j.artres.2015.11.001 ID - Akhtar2015 ER -