P9.08 THE ASSOCIATION BETWEEN METABOLIC SYNDROME AND AORTIC STIFFNESS IN GENERAL POPULATION
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- 10.1016/j.artres.2010.10.100How to use a DOI?
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Background: Despite being a cluster of conventional risk factors, metabolic syndrome (MetSy) has been recognized as independent predictor of cardiovascular diseases. We aimed to establish the association between metabolic syndrome and aortic pulse wave velocity (aPWV) as a measure of arterial stiffness in Czech general population.
Methods: 576 subjects (mean age 48.03y (SD 14.8)), 41.5% males), a Pilsen sub-sample of postMONICA survey, were included into cross-sectional study. APWV was estimated using Sphygmocor device, subjects with MetSy were identified using common NCEP-ATPIII definition.
Results: Subjects with MetSy showed signifficantly higher aPWV (9.02 vs. 7.42 m/sec, p<0.001), also if diabetic (8.75 vs. 7.18, p<0.001) or diabetic and hypertensive patients (7.96 vs. 6.84, p<0.001) were excluded from the analysis (p value adjusted for age).
The significance of association between MetSy and aPWV remained significant after adjustment for age, gender, current smoking, mean arterial pressure, serum glucose and other risk factors as potential confounders (b=−0,088, p=0.023).
Conclusion: In our sample of general population, we found that MetSy represents an additive risk factor of increased aortic stiffness independent of age, blood pressure, glucose status and other conventional factors.
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TY - JOUR AU - J. Strizova AU - O. Mayer AU - J. Filipovsky AU - J. Seidlerova PY - 2010 DA - 2010/12/02 TI - P9.08 THE ASSOCIATION BETWEEN METABOLIC SYNDROME AND AORTIC STIFFNESS IN GENERAL POPULATION JO - Artery Research SP - 174 EP - 174 VL - 4 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2010.10.100 DO - 10.1016/j.artres.2010.10.100 ID - Strizova2010 ER -