Obesity and hypertension (AH) are the most important related risk-factors of cardiovascular disease (CVD),so we examined differences in target-organ injury between obese and overweight hypertensive individuals. We studied 102 patients with mild to moderate AH (67males/35females, mean age 51,3±2,4years, BMI 30,9±1,9kg/m², duration of AH 4,6±1,4years). Examination included: ultrasound evaluation of left ventricular mass index (LVMMI), carotid artery IMT, of endothelial function of brachial artery; 24-hour BP monitoring. 49 overweight patients (25<BMI< 29,9kg/m²) were assigned to group 1 and 53 obese patients (30kg/m²) to gr 2.The groups were comparable by the age, duration of AH, daily mean BP values. Mean values of LVMMI (gr1:140,4±8,7gr/m; gr2:146,8±6,9gr/m) and IMT (gr1:1,02±0,03mm;gr2: 1,08±0,04mm) were certainly increased in obese patients compared with overweight ones (p< 0,001). Prevalence of carotid atherosclerosis was higher in gr2 (79%vs67%). Endothelium – dependent vasodilatation (EDVD) (gr1:7,6±0,5;gr2:7,01±0,3%) was significantly reduced in obese patients (p <0,01), but occurrence of endothelial dysfunction was almost equal (gr1:59;gr2:60%). Occurrence of left ventricular hypertrophy (LVH) and especially of eccentric type was higher in gr2 (86vs81%; 38vs22 %, respectively), of concentric hypertrophy in gr1 (59vs48%). Normal geometry occurred only in gr1(4%). Number of Non-Dippers was higher in gr2(72vs67 %),of Dippers in gr1(30vs14 %). BMI positively correlated with IMT (r = 0,25, p<0,02) and LVMMI (r = 0,41, p<0,01) and negatively with EDVD (r = −0,4, p<0,05).Thus, in Georgian obese hypertensive subjects we detected more pronounced and frequent target-organ injury (mostly eccentric LVH, carotid artery affection - IMC thickening, endothelial dysfunction) and disorders of BP circadian profile comparing with overweight ones.