Artery Research

Volume 6, Issue 4, December 2012, Pages 161 - 161

P1.38 RELATIONSHIP BETWEEN ANKLE BRACHIAL INDEX AND OTHER INDICES OF TARGET ORGAN DAMAGE IN HYPERTENSIVE PATIENTS

Authors
A. Szyndler1, T. Fabiszewska1, R. Nowak1, K. Czechowicz1, A. Dubiela1, K. Polonis1, W. Kucharska1, A. Rojek1, M. Hoffmann1, P. Boutouyrie2, S. Laurent2, K. Narkiewicz1
1Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland
2Department of Pharmacology, HEGP, APHP, INSERM U970, Université Paris Descartes, Paris, France
Available Online 17 November 2012.
DOI
10.1016/j.artres.2012.09.075How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Objective: Assessment of ankle brachial index (ABI) is a method of peripheral artery disease diagnosis. Its role has been established as a predictor of cardiovascular events. The role of ABI in the hypertensive patients without cardiovascular has not been studied. The aim of study was assessment of the relationship between ABI, target organ damage and ambulatory blood pressure in hypertensives.

Methods: 355 hypertensive patients (199 males, 56%) without history of renal or cardiovascular disease were examined. The ambulatory blood pressure (Spacelabs 90207), echocardiography (Vivid 7 Pro™), carotid intima-media thickness (IMT, ArtLab system), carotid-femoral pulse wave velocity (PWV) and central blood pressure (Sphygmocor) were measured. Ankle brachial index (blind Doppler), left ventricular mass index, and estimated glomerular filtration rate (eGFR, MDRD formula) were calculated.

Results: In the population ABI (mean 1.05 ± 0.11) was weakly related to central pulse pressure (r = −0.12; p = 0.02), but not to central SBP (r =0.04; p = NS). ABI was not linked to 24-h SBP (r = 0.03; p = NS), 24-h pulse pressure (r =0.08, p = NS), LVMI (r =0.01; p =NS, or eGFR (r = 0.10; p = NS). There was no correlation between ABI and other indices of arterial wall properties: IMT (r = 0.06; p = NS) or PWV (r =0.03; p = NS).

Conclusion: ABI is weakly related to central pulse pressure, but not to ambulatory or central blood pressure. ABI is not linked to other markers of cardiac and vascular damage in hypertensives without cardiovascular disease.

Journal
Artery Research
Volume-Issue
6 - 4
Pages
161 - 161
Publication Date
2012/11/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2012.09.075How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - A. Szyndler
AU  - T. Fabiszewska
AU  - R. Nowak
AU  - K. Czechowicz
AU  - A. Dubiela
AU  - K. Polonis
AU  - W. Kucharska
AU  - A. Rojek
AU  - M. Hoffmann
AU  - P. Boutouyrie
AU  - S. Laurent
AU  - K. Narkiewicz
PY  - 2012
DA  - 2012/11/17
TI  - P1.38 RELATIONSHIP BETWEEN ANKLE BRACHIAL INDEX AND OTHER INDICES OF TARGET ORGAN DAMAGE IN HYPERTENSIVE PATIENTS
JO  - Artery Research
SP  - 161
EP  - 161
VL  - 6
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.09.075
DO  - 10.1016/j.artres.2012.09.075
ID  - Szyndler2012
ER  -