Artery Research

Volume 24, Issue C, December 2018, Pages 112 - 112

P114 APPLICATION AND REPLICABILITY OF BILATERAL AND SIMULTANEOUS MULTIPLE ARTERIAL BLOODPRESSURE MEASUREMENTS IN SEDENTARY AND PHYSICALLY ACTIVE PROFESSIONS

Authors
Eric de Groot1, 2
1Imagelabonline and Cardiovascular, Eindhoven, the Netherlands
2Academic Medical Centre, Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam, the Netherlands
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.167How to use a DOI?
Abstract

Background: Lack of physical activity is endemic in office life. Sedentary associated disorders include general adaptation syndrome (‘stress’), musculoskeletal, cardiovascular, metabolic and overweight. These conditions provoke absenteeism. Purpose: We evaluated applicability and replicability of a novel multi-arterial blood pressure device in healthy sedentary and physically active, non-sedentary individuals in their professional environment.

Methods: Arterial properties of 20 asymptomatic (46,0(SD12.9) years, 6 sedentary and 14 non-sedentary volunteers) were assessed twice. A Vascassist device and Vasometrix software (iSYMED/Adiphea, Butzbach, Germany) was used. Ankle-brachial index (ABI) and pulse wave velocity (PWV) were calculated. Central Aortic Pressure (CAP) and Vascular Age (VA) were calculated using general transfer functions (GTF’s).

Results: Initial RR’s were raised (134(SD15.6)/81(12.6) versus 124(10.6)/73(10.8) mmHg in repeat assessments, p < 0.001). Intial and repeat ABI’s (1.20(SD0.08), 1.20(0.08)%, r = 0.78), and PWV’s (10.3(SD1.6), 10.2(1.4)m/s, r = 0.85) were highly correlated. So were CAP’s (116.3(9.4) and 115.5 (9.4mmHg), and VA’s (39,7 (12.8) and 41.0 (11.9)years). Sedentary subjects showed increased initial SBP’s (Δ9.0mmHg, p = 0.03), DBP’s (Δ14.2 mmHg, p < 0.001), and VA’s (Δ11.1yrs, p = 0.04), but not in repeat assessments (all p’s > 0.1). ABI’s in the active were lower (1.17(0.05) vs. 1.28(0.07)%: p’s < 0.001), as were diastolic CAP’s (Δ’s 14.3 and 12.5 mmHg; p’s<0.01). ΔPWV’s were indifferent.

Conclusions: As in clinic, in corporate environments ‘white coat’ hypertension is observed and can be considered an autonomic response being more outspoken in the sedentary. RR, ABI, PWV, CAP and VA proved highly replicable endpoints. Simultaneous multiple arterial blood pressure assessments and validated GTF modelling create robust functional and structural arterial endpoints for efficacy evaluation of pharmaceutical, nutriceutical and life-style cardioavascular health interventions.

Open Access
This is an open access article distributed under the CC BY-NC license.

Journal
Artery Research
Volume-Issue
24 - C
Pages
112 - 112
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.167How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Eric de Groot
PY  - 2018
DA  - 2018/12/04
TI  - P114 APPLICATION AND REPLICABILITY OF BILATERAL AND SIMULTANEOUS MULTIPLE ARTERIAL BLOODPRESSURE MEASUREMENTS IN SEDENTARY AND PHYSICALLY ACTIVE PROFESSIONS
JO  - Artery Research
SP  - 112
EP  - 112
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.167
DO  - 10.1016/j.artres.2018.10.167
ID  - deGroot2018
ER  -