Artery Research

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Volume 24, Issue C, December 2018, Pages 130 - 130

P169 RELATIONSHIP BETWEEN COMMON CAROTID DISTENSIBILITY/AORTIC STIFFNESS AND LEFT VENTRICULAR MORPHOLOGY AND FUNCTION IN RHEUMATOLOGIC PATIENTS

Authors
Michele Bevilacqua1, 2, Andrea Dalbeni2, Angela Tagetti2, Luca Gomarasca2, Giovanni Orsolini3, Andrea Giollo3, Maurizio Rossini3, Ombretta Viapiana3, Giovanni Cioffi4, Pietro Minuz2, Cristiano Fava2
1University of Verona, Italy
2Division of General Medicine and Hypertension, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
3Division of Rheumatology, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy
4Department of Cardiology, Villa Bianca Hospital, Trento, Italy
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.222How to use a DOI?
Abstract

Introduction: Arterial stiffness is known to be associated with atherosclerosis, cardiac remodelling and cardiovascular diseases. In recent studies, common carotid artery rigidity was seen to better predict cardiac morphology and function if compared to aortic parameters. The aim of the study was to determine the relation between carotid/aortic stiffness indices and the main echocardiographic measures in patients with rheumatological disease.

Methods: 208 participants were evaluated (57,4 ± 11,4 yr; males = 36,1%); 65,9% were previously diagnosed with rheumatoid arthritis, 20,2% with psoriatic arthritis and 13,9% with ankylosing spondylitis. In each subjects medical history, use of drugs and glico-metabolic status was assessed. Echocardiography, blood pressure (BP) measurement and carotid ultrasonography were performed. Carotid Distensibility (CD) and Aortic Stiffness (AoS) were measured as indices of arterial stiffness.

Results: Mean Left Ventricular Mass indexed by body surface area (LVM/BSA) and Relative Wall Thickness (RWT) were 98,8 ± 20,7 g/m2 and 0,46 ± 0,06, respectively. In multiple regression analysis, DC was correlated with age (β = 0,325, p < 0,0001) and mean BP (β = 0,502, p < 0,0001) while AoS was not associated with any anthropometric, anamnestic and vascular parameters. DC has been seen to inversely correlate with LVM/BSA (r = −0,20, p = 0,005), Intraventricular Septum and Posterior Wall Thickenss; a direct correlation between AoS and left E/e’ (a diastolic function indicator) has emerged (r = 0,191, p = 0,007).

Conclusion: Results are consistent with a possible predictive role of DC assessment in left cardiac hypertrophy and remodelling and a direct link between AoS and left ventricular diastolic function.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
130 - 130
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.222How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Michele Bevilacqua
AU  - Andrea Dalbeni
AU  - Angela Tagetti
AU  - Luca Gomarasca
AU  - Giovanni Orsolini
AU  - Andrea Giollo
AU  - Maurizio Rossini
AU  - Ombretta Viapiana
AU  - Giovanni Cioffi
AU  - Pietro Minuz
AU  - Cristiano Fava
PY  - 2018
DA  - 2018/12/04
TI  - P169 RELATIONSHIP BETWEEN COMMON CAROTID DISTENSIBILITY/AORTIC STIFFNESS AND LEFT VENTRICULAR MORPHOLOGY AND FUNCTION IN RHEUMATOLOGIC PATIENTS
JO  - Artery Research
SP  - 130
EP  - 130
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.222
DO  - 10.1016/j.artres.2018.10.222
ID  - Bevilacqua2018
ER  -