9.8 NEAR INFRARED SPECTROSCOPY (NIRS) CAN DETECT IMPROVEMENTS IN ARTERIAL FUNCTION FOLLOWING 6-MONTHS OF MARATHON TRAINING
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Background: Endurance training improves vascular function and skeletal muscle perfusion. NIRS can measure changes in oxygenated haemoglobin (oxy-Hb) in the skeletal muscle microvascular bed. Therefore, combined with arterial occlusion, NIRS has the potential to assess microvascular function within skeletal muscle. However, NIRS measurements are strongly influenced by adipose tissue thickness (ATT) at the measurement site.
Methods: Vascular function was tested in healthy individuals prior to marathon training oxy-Hb changes were measured by NIRS (Portamon, Artinis) during a 30-second arterial occlusion and the subsequent hyperemic response. ATT was assessed at the site of measurement using ultrasound (Vivid I, GE).
Participants underwent the same test after completing the marathon. Post-occlusive time-to-peak oxy-Hb response and Δoxy-Hb concentration were compared pre- and post-marathon and the effect of ATT on each parameter was assessed. Results are meanSD a paired t-test was used for comparison and β-coefficients used to compare the ATT relationships.
Results: 34 participants (18=male, 30±3 years old) completed vascular testing and ATT measurements. The Δoxy-Hb value was more strongly attenuated by ATT than time-to-peak oxy-Hb (β-coefficients: −0.58, p<0.0001 and −0.14, p=0.45, respectively). 27 participants (15=male, 313 years old) completed the marathon and underwent testing at both time points. Time-to-peak hyperemic response was significantly faster post-marathon (Δ1.95±4.07seconds, p=0.01) but there was no difference in Δoxy-Hb(0.83±6.23 μM, p=0.5).
Conclusions: Endurance training has a positive effect on reperfusion rates following short duration ischemia. Improvements can be detected using NIRS to measure oxy-Hb changes. Comparing the time-to-peak response overcomes some of the limitations of ATT on the NIRS measurements.
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Cite this article
TY - JOUR AU - Siana Jones AU - Andrew D’Silva AU - Alun Hughes PY - 2016 DA - 2016/11/24 TI - 9.8 NEAR INFRARED SPECTROSCOPY (NIRS) CAN DETECT IMPROVEMENTS IN ARTERIAL FUNCTION FOLLOWING 6-MONTHS OF MARATHON TRAINING JO - Artery Research SP - 70 EP - 70 VL - 16 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2016.10.075 DO - 10.1016/j.artres.2016.10.075 ID - Jones2016 ER -