Artery Research

Volume 12, Issue C, December 2015, Pages 33 - 34

P7.17 DISASSOCIATION OF BLOOD PRESSURE FROM AORTIC RESERVOIR CHARACTERISTICS BETWEEN THE AORTA AND RADIAL ARTERIES

Authors
Xiaoqing Peng*1, Martin Schultz1, Justin Davies2, Dean Picone1, Andrew Black3, Nathan Dwyer3, Phil Roberts-Thomson3, James Sharman1
1Menzies Institute for Medical Research, University of Tasmania, Hobart, TAS, Australia
2International Centre for Circulatory Health, Imperial College, London, W2 1LA, UK
3Royal Hobart Hospital, Hobart, TAS, Australia
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.320How to use a DOI?
Abstract

Background: Aortic reservoir pressure (RP) and excess pressure (XSP) predict cardiovascular events independent of clinic blood pressure (BP). It is unknown whether RP and XSP change in magnitude from the central to peripheral large arteries where conventional BP is measured. This information has implications for understanding the arterial pathophysiology. This study aimed to determine the change in RP and XSP from the aorta to the brachial and radial arteries, as well as associations of these indices with BP.

Methods: 23 participants (aged 65±9 years, 70% male) undergoing clinically indicated cardiac angiography had intra-arterial pressure waveforms measured via fluid-filled catheter in the ascending aorta, brachial (mid-humorous) and radial arteries (wrist) by catheter pull-back. RP and XSP (using previously published algorithms), and BP were derived from pressure waveforms at each location.

Results: There was a non-significant decrease in RP from the aorta to the brachial and radial arteries (112±22, 109±18, 103±17 mmHg respectively, p=0.242). On the other hand, XSP significantly increased from the aorta to the brachial and radial arteries (21±8, 41±15, 58±19 mmHg respectively, p<0.001). However, neither RP or XSP (either measured by peak or integral) were significantly associated with either systolic BP or pulse pressure at any arterial location (p>0.05 all).

Conclusion: RP is relatively constant between the aorta and radial arteries, whereas XSP increases significantly. Neither indices are related to BP, thus supporting the independent pathophysiological relevance of aortic reservoir characteristics.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
33 - 34
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.320How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - Xiaoqing Peng*
AU  - Martin Schultz
AU  - Justin Davies
AU  - Dean Picone
AU  - Andrew Black
AU  - Nathan Dwyer
AU  - Phil Roberts-Thomson
AU  - James Sharman
PY  - 2015
DA  - 2015/11/23
TI  - P7.17 DISASSOCIATION OF BLOOD PRESSURE FROM AORTIC RESERVOIR CHARACTERISTICS BETWEEN THE AORTA AND RADIAL ARTERIES
JO  - Artery Research
SP  - 33
EP  - 34
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.320
DO  - 10.1016/j.artres.2015.10.320
ID  - Peng*2015
ER  -