Artery Research

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Volume 25, Issue Supplement 1, December 2019, Pages S15 - S15

2.6 Validation of the Measurement of Aortic Stiffness by the CARDIS Laser Doppler Vibrometer

Authors
Louise Marais1, *, Hakim Khettab1, Yanlu Li2, Patrick Segers3, Roel Baets2, Koen Reesink4, Soren Aasmul5, Mirko De Melis5, Pierre Boutouyrie1
1Inserm U970 - PARCC, Paris, France
2Ghent University, Ghent, Belgium
3bioMMeda - Institute Biomedical Technology, Ghent University, Ghent, Belgium
4CARIM, Maastricht University Medical Center, Maastricht, The Netherlands
5Medtronic Bakken Research Center, Maastricht, The Netherlands
*Corresponding author. Email: louise.marais@inserm.fr
Corresponding Author
Louise Marais
Available Online 17 February 2020.
DOI
10.2991/artres.k.191224.011How to use a DOI?
Abstract

Purpose: There is a need for new tools to screen large populations for cardiovascular disease risk. The CARDIS consortium (European Union H2020 funding) developed an easy-to-use, non-contact device for measuring carotid to femoral pulse wave velocity (cfPWV). It consists in a laser doppler vibrometer (LDV), which measures skin vibrations induced by large artery pulses. Pulse waveforms can be tracked and transit time (TT) can be calculated. This study aimed at comparing LDV-cfPWV with the reference cfPWV measured by applanation tonometry (Sphygmocor).

Methods: We included 100 patients with mild to stage 3 hypertension, controlled or not. Reflective tapes were applied on the carotid and femoral arteries to measure LDV-cfPWV 4 times. TT was measured by the foot-to-foot method from the maximum of 2nd derivative using in-house algorithms not requiring ECG, and compared to Sphygmocor (3 acquisitions).

Results: LDV-cfPWV was obtained in 100% of patients. Mean age was 47 ± 19 (range 19–85). Hypertensives were well controlled (119/65 mmHg). Mean value of LDV-cfPWV was 6.9 ± 1.7 m/s, compared to 7.5 ± 1.7 m/s with Sphygmocor, bias 0.65 ± 1.27, R value 0.72 (Figure 1), which qualifies agreement as acceptable according to the guidelines from the ARTERY Society [1]. Reproducibility was good with a median coefficient of variation of 5.6%. LDV-cfPWV showed similar associations with age and blood pressure than tonometry (r = 0.68, p < 0.001 and r = 0.44, p < 0.001, respectively).

Conclusion: Non-contact measurement of pulse wave velocity by laser doppler vibrometry is feasible, fast and easy to perform, and provides acceptable agreement with reference technique.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Reference

[1]IB Wilkinson, CM McEniery, G Schillaci, P Boutouyrie, P Segers, A Donald, et al., ARTERY Society guidelines for validation of non-invasive haemodynamic measurement devices: Part 1, arterial pulse wave velocity, Artery Res, Vol. 4, 2010, pp. 34-40.
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Journal
Artery Research
Volume-Issue
25 - Supplement 1
Pages
S15 - S15
Publication Date
2020/02/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191224.011How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - Louise Marais
AU  - Hakim Khettab
AU  - Yanlu Li
AU  - Patrick Segers
AU  - Roel Baets
AU  - Koen Reesink
AU  - Soren Aasmul
AU  - Mirko De Melis
AU  - Pierre Boutouyrie
PY  - 2020
DA  - 2020/02/17
TI  - 2.6 Validation of the Measurement of Aortic Stiffness by the CARDIS Laser Doppler Vibrometer
JO  - Artery Research
SP  - S15
EP  - S15
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.011
DO  - 10.2991/artres.k.191224.011
ID  - Marais2020
ER  -