P57 In Patients with Chronic Descending Aorta Dissection the Maximum Systolic Flow Deceleration Rate in the False Lumen is Associated with Aortic Dilatation: a 4D-flow MRI Study
- 10.2991/artres.k.191224.088How to use a DOI?
Background: Aortic type B dissection is a life-threating condition in which blood flows between aortic wall layers. Despite a role for morphological variables, such as entry tear location and dimension, in the prediction of progressive false lumen (FL) dilation has been suggested, the role of flow characteristics has not been studied due to the unavailability of proper flow descriptions. Now that 4D phase-contrast magnetic resonance imaging (4D-flow MRI) allows for the evaluation of flow field with unprecedented detail, we tested whether flow deceleration in the FL, being a marker of occluded flow exit, is related to FL dilation.
Methods: In 29 patients with a patent FL and with a retrospective CT-based follow-up >3 years underwent 4D-flow MRI. Flow acceleration in the FL was calculated in a standardized sub-volume of the descending aorta. The maximum systolic flow deceleration rate (MSDR) was quantified as maximum minus minimum acceleration during systole divided by the corresponding time interval (Figure 1a).
Results: Demographic and clinical variables were similar among growth-rate (GR) tertiles. MSDR was statistically different in patients with a GR <1 mm/year (group 1) compared to fast-dilating patients (groups 2, 3) (Figure 1c). MSDR showed a positive linear correlation with GR (R = 0.48; p = 0.008) (Figure 1b).
Conclusion: The intensity of flow deceleration in the FL of chronic type B dissection is related to its retrospective growth rate. If confirmed in prospective studies, this marker may be useful to discriminate aorta enlargement and identify high-risk patients.
- © 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - JOUR AU - Andrea Guala AU - Aroa Ruiz-Muñoz AU - Lydia Duz-Santoy AU - Gisela Teixido-Tura AU - Chiara Granato AU - Augusto Sao-Aviles AU - Lucia La Mura AU - Angela Lopez-Sainz AU - Maria Luz Servato AU - Arturo Evangelista AU - Ignacio Ferreira AU - Jose Rodriguez-Palomares PY - 2020 DA - 2020/02/17 TI - P57 In Patients with Chronic Descending Aorta Dissection the Maximum Systolic Flow Deceleration Rate in the False Lumen is Associated with Aortic Dilatation: a 4D-flow MRI Study JO - Artery Research SP - S98 EP - S98 VL - 25 IS - Supplement 1 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.191224.088 DO - 10.2991/artres.k.191224.088 ID - Guala2020 ER -