P26 Ascending Aorta Longitudinal Strain is not Altered in Bicuspid Aortic Valve Patients
- 10.2991/artres.k.191224.060How to use a DOI?
Background: Impaired ascending aorta (AAo) longitudinal strain, a marker of AAo deformation due to aorto-ventricular mechanical interaction, is related to progressive dilation and aortic events in Marfan syndrome . Whether the high prevalence of dilation in bicuspid aortic valve (BAV) is due to intrinsically-altered aortic wall properties  or hemodynamic  is widely-discussed . Whether AAo longitudinal strain is altered in BAV patients has never been assessed.
Methods: One-hundred five BAV patients, 47 patients with AAo dilation and tricuspid aortic valve (TAV) and 31 healthy volunteers, free from previous cardiac/aortic surgery, dissection and moderate/severe valvular disease had cine MR images to compute AAo longitudinal strain .
Results: Compared to healthy volunteers, the 25 non-dilated (z-score < 2) BAV patients were older (p < 0.001), had higher systolic blood pressure (SBP, p = 0.001), clinically-meaningless (BAV z-score = 0.74 ± 1.1) larger AAo diameter (p < 0.001) and similar diastolic blood pressure (DBP), BSA, stroke volume and heart rate. AAo longitudinal strain was lower in non-dilated BAV compared to healthy volunteers (13.7 vs 10.3%, p = 0.008) but this difference was not significant after correction for age. Compared to dilated TAV, dilated BAV patients were younger (p < 0.001), had lower BSA (p = 0.010) and AAo diameter (p = 0.003), higher DBP (p = 0.032) and similar SBP, stroke volume and heart rate. AAo longitudinal strain was higher in dilated BAV compared to dilated TAV (10 vs 7.2%, p < 0.001) but this difference was not significant after correction for age, BSA and DBP.
Conclusion: AAo longitudinal strain is similar in BAV and TAV matched for aortic dilation.
- © 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - JOUR AU - Andrea Guala AU - Lydia Dux-Santoy AU - Gisela Teixido-Tura AU - Aroa Ruiz-Muñoz AU - Laura Madrenas AU - Minerva Gandara AU - Augusto Sao-Aviles AU - Filipa Valente AU - Laura Galian-Gay AU - Laura Gutierrez AU - Teresa Gonzalez-Alujas AU - Ignacio Ferreira AU - Arturo Evangelista AU - Jose Rodriguez-Palomares PY - 2020 DA - 2020/02/17 TI - P26 Ascending Aorta Longitudinal Strain is not Altered in Bicuspid Aortic Valve Patients JO - Artery Research SP - S69 EP - S69 VL - 25 IS - Supplement 1 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.191224.060 DO - 10.2991/artres.k.191224.060 ID - Guala2020 ER -