Artery Research

Volume 26, Issue Supplement 1, December 2020, Pages S2 - S2

YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood

Authors
Chloe Park1, *, Siana Jones1, Suzanne Williams1, Alicja Rapala1, Hannah Taylor1, Laura Howe2, Abigail Fraser2, Nish Chaturvedi1, Alun Hughes1
1University College London
2University of Bristol
*Corresponding author. Email: chloe.park@ucl.ac.uk
Corresponding Author
Chloe Park
Available Online 31 December 2020.
DOI
10.2991/artres.k.201209.002How to use a DOI?
Keywords
Adolescents; cardiovascular-aging; birth-cohort; sex-differences
Abstract

Purpose: To define and compare cardiovascular (CV) health scores (CHS) from adolescence (17 yrs) to emerging adulthood (24 yrs) using longitudinal data from a large British birth cohort.

Methods: 3142 participants from the Avon Longitudinal Study of Parents and Children (ALSPAC) study attended clinical investigations at 17.8 ± 0.4 yrs and 24.0 ± 0.8 yrs (38% male). CV health was assessed using smoking status, body mass index (BMI), plasma glucose, cholesterol, sitting brachial blood pressure, left ventricle (LV) hypertrophy, arterial stiffness (carotid-to-femoral pulse wave velocity) and atherosclerosis (carotid intima-media thickness) metrics. Prevalence was stratified into poor (0_points), intermediate (1_point) and ideal (2_points) health categories and a composite, individual-level CHS for all 8 metrics was calculated (total range, 0–16 points). Prevalence of ideal health was assessed using ANOVA and linear mixed modelling assessed age##sex modifications.

Results: Overall CHS was high at 17 yrs but from 17–24 yrs the proportion of ideal scores decreased for all metrics, in both sexes (Table). The average overall CHS decreased from 14.97 ± 1.1 to 13.99 ± 1.4 in males (p < 0.0001) and 14.82 ± 1.2 to 14.28 ± 1.4 in females (p < 0.0001, age##sex p = 0.0001). Significant sex differences were observed in the proportion of individuals with ideal health at both ages, with males having a higher CHS than females at 17 yrs but a lower CHS at 24 yrs.

Male Female Sex differences



Age 17 yrs 24 yrs 17 yrs 24 yrs 17 24 Age##sex







Score 0 1 2 0 1 2 p 0 1 2 0 1 2 p p p p
Smoking 22.6 19.3 58.1 27.8 35.6 36.6 <0.0001 27.8 24.3 47.9 25.7 36.5 37.8 <0.0001 <0.0001 0.29 <0.0001
BMI 4.9 13.3 82.1 10.4 30.0 59.6 <0.0001 6.7 15.4 77.9 14.6 21.5 63.8 <0.0001 0.006 0.97 0.02
Glucose 0.4 9.1 90.5 0.6 34.7 64.7 <0.0001 0.3 2.6 97.1 0.4 16.1 83.5 <0.0001 <0.0001 <0.0001 <0.0001
Cholesterol 0.0 1.5 98.5 2.1 11.7 86.2 <0.0001 0.1 4.5 95.4 3.0 13.6 83.3 <0.0001 0.002 0.07 0.14
Blood pressure 0.2 0.5 99.3 0.6 5.4 94.0 <0.0002 0.3 1.7 98.0 0.7 4.1 95.2 <0.0001 0.001 0.3 0.0001
LV hypertrophy 0.6 0.6 98.9 1.4 3.7 94.8 <0.0001 0.5 1.6 97.8 1.1 3.8 95.1 <0.0001 0.43 0.75 0.2
Arterial stiffness 0.5 0.9 98.6 4.8 6.7 88.5 <0.0001 0.0 0.4 99.6 1.8 2.9 95.4 <0.0001 0.01 <0.0001 <0.0001
Atherosclerosis 0.0 0.9 99.1 0.0 1.2 98.8 0.0005 0.0 0.3 99.7 0.0 0.4 99.6 0.9 0.07 0.04 0.6
Average CHS 14.97 ± 1.1 13.99 ± 1.4 <0.0001 14.82 ± 1.2 14.28 ± 1.4 <0.0001 0.01 <0.0001 <0.0001

Data are % of participants in each category for each risk factor. 0 = poor, 1 = intermediate and 2 = ideal. Age##sex p value for modification.

Conclusions: Despite being relatively early in the life-course, CV health declines from 17 yrs to 24 yrs in both sexes, and more substantially in males. Emerging adulthood is a distinct period of lifestyle change and an important time to control CV risk factors to improve future CV health.

Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Journal
Artery Research
Volume-Issue
26 - Supplement 1
Pages
S2 - S2
Publication Date
2020/12/31
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.201209.002How to use a DOI?
Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Chloe Park
AU  - Siana Jones
AU  - Suzanne Williams
AU  - Alicja Rapala
AU  - Hannah Taylor
AU  - Laura Howe
AU  - Abigail Fraser
AU  - Nish Chaturvedi
AU  - Alun Hughes
PY  - 2020
DA  - 2020/12/31
TI  - YI 1.2 Ideal Cardiovascular Health Score Declines from Adolescence to Emerging Adulthood
JO  - Artery Research
SP  - S2
EP  - S2
VL  - 26
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.201209.002
DO  - 10.2991/artres.k.201209.002
ID  - Park2020
ER  -