Artery Research

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Volume 26, Issue Supplement 1, December 2020, Pages S65 - S65

P.43 The Association Between Early Vascular Aging and Cyclothymic Affective Temperament

Authors
Milan Vecsey-Nagy1, *, Bálint Szilveszter1, Márton Kolossváry1, Xénia Gonda2, 3, 4, Zoltán Rihmer3, Béla Merkely1, Pál Maurovich-Horvat1, 5, János Nemcsik6, 7
1Varosmajor Heart And Vascular Center, Semmelweis University
2Department of Pharmacodynamics, Semmelweis University
3Department of Psychiatry and Psychotherapy, Semmelweis University
4MTA-SE Neurochemistry Research Group
5Medical Imaging Centre, Semmelweis University
6Department of Family Medicine, Semmelweis University
7Health Service of Zugló (ZESZ)
*Corresponding author. Email: vnagymilan@gmail.com
Corresponding Author
Milan Vecsey-Nagy
Available Online 31 December 2020.
DOI
10.2991/artres.k.201209.055How to use a DOI?
Keywords
Vascular age; affective temperaments
Abstract

Objectives: Affective temperaments (depressive, anxious, irritable, hyperthymic, cyclothymic) are regarded as the biologically stable core of personality, and accumulating data implies their relationship with cardiovascular diseases. There are currently limited data on the association of affective temperaments and early vascular aging. The aim of our study was to assess the potential relationship of affective temperaments and vascular age, as assessed by coronary CT.

Methods: In our current cross-sectional study, 209 patients referred to coronary computed tomography angiography (CCTA) due to suspected coronary artery disease (CAD), were included. After the evaluation of medical history and demographic parameters, all patients completed the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A) and the Beck Depression Inventory (BDI). Vascular age was estimated using coronary artery calcium (CAC) score and we calculated its difference from chronological age for each patient. Linear regression analysis was applied to identify predictors of early vascular aging in the entire cohort and in male and female sub-populations, separately.

Results: The independent predictors of early vascular aging were female sex (B = −10.82 [95% CI: −15.30 – −6.33]), diabetes mellitus (B = 7.16 [95% CI: 1.20 – 13.12]) and dyslipidemia (B = −8.28 [95% CI: 3.94 – 12.62]). Further assessing gender differences, cyclothymic temperament score proved to be an independent predictor of early vascular aging in women (B = 0.89 [95% CI: 0.04 – 1.75]), while this association was absent in men.

Conclusions: Our results suggest that cyclothymic affective temperament contribute to early vascular aging in women.

Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Artery Research
Volume-Issue
26 - Supplement 1
Pages
S65 - S65
Publication Date
2020/12/31
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.201209.055How to use a DOI?
Copyright
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - JOUR
AU  - Milan Vecsey-Nagy
AU  - Bálint Szilveszter
AU  - Márton Kolossváry
AU  - Xénia Gonda
AU  - Zoltán Rihmer
AU  - Béla Merkely
AU  - Pál Maurovich-Horvat
AU  - János Nemcsik
PY  - 2020
DA  - 2020/12/31
TI  - P.43 The Association Between Early Vascular Aging and Cyclothymic Affective Temperament
JO  - Artery Research
SP  - S65
EP  - S65
VL  - 26
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.201209.055
DO  - 10.2991/artres.k.201209.055
ID  - Vecsey-Nagy2020
ER  -