Clinical Hematology International

Volume 1, Issue 1, March 2019, Pages 52 - 57

Idiopathic Aplastic Anemia: An Update

Authors
Elena E. Solomou*
Assistant Professor, Internal Medicine-Hematology, University of Patras Medical School, Rion 26500, Greece

Peer review is under the responsibility of IACH

Corresponding Author
Elena E. Solomou
Received 1 March 2019, Accepted 17 March 2019, Available Online 1 April 2019.
DOI
https://doi.org/10.2991/chi.d.190321.002How to use a DOI?
Keywords
Acquired aplastic anemia; Bone marrow failure
Abstract

“Bone marrow failure” encompass all the conditions and syndromes in which there are qualitative or quantitative disorders of one or more lineages (erythroid, myelomonocytic, and/or megakaryocytic). A few years ago, the pathophysiology of these syndromes was completely unknown. Today we have better knowledge for these diseases, allowing the development of new treatment options and the improvement of patients' outcome. Acquired bone marrow failure syndromes include myelodysplastic syndromes, aplastic anemia, paroxysmal nocturnal hemoglobinuria, idiopathic neutropenia and large granular leukemia. All these syndromes share some common features and pathophysiology. The most important feature is the possibility of clonal evolution and progression into acute myelogenous leukemia, and open questions still remain on how to prevent evolution in these patients.

Copyright
© 2019 International Academy for Clinical Hematology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Clinical Hematology International
Volume-Issue
1 - 1
Pages
52 - 57
Publication Date
2019/04/01
ISSN (Online)
2590-0048
DOI
https://doi.org/10.2991/chi.d.190321.002How to use a DOI?
Copyright
© 2019 International Academy for Clinical Hematology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Elena E. Solomou
PY  - 2019
DA  - 2019/04/01
TI  - Idiopathic Aplastic Anemia: An Update
JO  - Clinical Hematology International
SP  - 52
EP  - 57
VL  - 1
IS  - 1
SN  - 2590-0048
UR  - https://doi.org/10.2991/chi.d.190321.002
DO  - https://doi.org/10.2991/chi.d.190321.002
ID  - Solomou2019
ER  -