Proceedings of the 2nd Aceh International Dental Meeting 2021 (AIDEM 2021)

<Previous Article In Volume
Next Article In Volume>

Effects of Extract Endophytic Fungi Aspergillus sp. in Denture Adhesives of Acrylic Resins Related to the Surface Roughness and Candida Albicans Virulence

Authors
Okmes Fadriyanti1, 5, *, Ismet Danial Nasution2, Widowati Siswomihardjo3, Dian Handayani4
1Doctoral Program, Faculty of Dentistry, Sumatera Utara University, Medan, Indonesia,
2Department of Prosthodontics, Faculty of Dentistry, Sumatera Utara University, Medan, Indonesia
3Department of Dental Materials, Faculty of Dentistry, Gadjah Mada University, Yogyakarta, Indonesia
4Sumatera Biota Laboratory, Faculty of Pharmacy, Andalas University, Padang, Indonesia
5Department of Prosthodontia, Faculty of Dentistry, Baiturrahmah University, Padang, Indonesia
*Correspondence address; Email: okmes_f@yahoo.co.id
Corresponding Author
Okmes Fadriyanti
Available Online 3 March 2022.
DOI
10.2991/ahsr.k.220302.011How to use a DOI?
Keywords
Extract Aspergillus sp.; Denture adhesive; Bio-tolerance; C. albicans; Surface roughness
Abstract

Antifungal treatment is currently a serious problem because resistance and attachment of C. albicans often occur and can have an effect on the acrylic resin surface. One of them is adding antifungal concentration from the extract of endophyte fungi Aspergillus sp. contains chemical compounds that can inhibit C. albicans. The study aimed was to effect of extract of endophyte fungi Aspergillus sp. in denture adhesives of acrylic resins related to the surface roughness and C.albicans virulence. The research method was to extract the endophytic fungi Aspergillus sp. bio-tolerance test and measure the surface roughness of acrylic resin. The research sample used heat polymerized acrylic resin, namely the denture adhesive treatment group with a predetermined concentration, the control group using commercial denture adhesive and, added nystatin, each group suspended C. albicans for 24, 48 and 72 hours. Analysis using ANOVA. Bio-tolerance activity of Aspergillus sp. to C. albicans was the best at concentrations of 12.5% and 25%, the strongest occurred at 24 hours of incubation. The lower the concentration, the better it is to prevent surface roughness of the acrylic resin, but there is no difference in the surface roughness of acrylic resin concerning concentration and incubation time. Aspergillus sp. endophytic fungi extract. on denture adhesives can inhibit the activity and interaction of C. albicans as well as the surface roughness of acrylic resin which is better than synthetic antifungals.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Download article (PDF)

<Previous Article In Volume
Next Article In Volume>
Volume Title
Proceedings of the 2nd Aceh International Dental Meeting 2021 (AIDEM 2021)
Series
Advances in Health Sciences Research
Publication Date
3 March 2022
ISBN
10.2991/ahsr.k.220302.011
ISSN
2468-5739
DOI
10.2991/ahsr.k.220302.011How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Okmes Fadriyanti
AU  - Ismet Danial Nasution
AU  - Widowati Siswomihardjo
AU  - Dian Handayani
PY  - 2022
DA  - 2022/03/03
TI  - Effects of Extract Endophytic Fungi Aspergillus sp. in Denture Adhesives of Acrylic Resins Related to the Surface Roughness and Candida Albicans Virulence
BT  - Proceedings of the 2nd Aceh International Dental Meeting 2021 (AIDEM 2021)
PB  - Atlantis Press
SP  - 61
EP  - 66
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220302.011
DO  - 10.2991/ahsr.k.220302.011
ID  - Fadriyanti2022
ER  -