Concentrations of Trace Elements in Different Types of Gallstones and Their Effects on Gallstone Formation
Yue Zhang, Chongyu Zhang, Da Guo, Xiaojun Huang, Junfa Xue, Jianming Ouyang
Available Online July 2016.
- https://doi.org/10.2991/bbe-16.2016.51How to use a DOI?
- Gallstones, Trace Element, ICP-AES, Cholesterol, Bile Pigment.
- Purpose: To study the concentrations of trace metals and nonmetals elements in different types of gallstones (cholesterol-, pigment-, mixed- and calcium carbonate type) and to explore the formation mechanisms of gallstones. Method: Inductively coupled plasma emission spectrometer (ICP-AES) was used to determine the concentrations of calcium, manganese, magnesium, iron, copper, zinc, sulfur, and phosphorus. Results: Calcium, copper, sulfur and phosphorus play important roles in the formation of pigment stones. High concentrations of Cu2+ and Ca2+ ions can coordinate with bilirubin to form calcium bilirubinate and copper bilirubinate, respectively; phosphorus and sulfur suggest the presence of proteins in gallstones, and some proteins (such as mucin) can promote the formation of gallstones. Conclusions: The contents of metal and nonmetal elements in gallstones can accurately be detected using ICP-AES. The formation of different types of gallstones is closely related to the difference of these elements. This study is of great significance to reveal the cause of gallstones formation.
- Open Access
- This is an open access article distributed under the CC BY-NC license.
Cite this article
TY - CONF AU - Yue Zhang AU - Chongyu Zhang AU - Da Guo AU - Xiaojun Huang AU - Junfa Xue AU - Jianming Ouyang PY - 2016/07 DA - 2016/07 TI - Concentrations of Trace Elements in Different Types of Gallstones and Their Effects on Gallstone Formation BT - International Conference on Biomedical and Biological Engineering PB - Atlantis Press SP - 331 EP - 336 SN - 2468-5747 UR - https://doi.org/10.2991/bbe-16.2016.51 DO - https://doi.org/10.2991/bbe-16.2016.51 ID - Zhang2016/07 ER -