Concentrations of Trace Elements in Different Types of Gallstones and Their Effects on Gallstone Formation
- 10.2991/bbe-16.2016.51How to use a DOI?
- Gallstones, Trace Element, ICP-AES, Cholesterol, Bile Pigment.
Purpose: To study the concentrations of trace metals and nonmetals elements in different types of gallstones (cholesterol-, pigment-, mixed- and calcium carbonate type) and to explore the formation mechanisms of gallstones. Method: Inductively coupled plasma emission spectrometer (ICP-AES) was used to determine the concentrations of calcium, manganese, magnesium, iron, copper, zinc, sulfur, and phosphorus. Results: Calcium, copper, sulfur and phosphorus play important roles in the formation of pigment stones. High concentrations of Cu2+ and Ca2+ ions can coordinate with bilirubin to form calcium bilirubinate and copper bilirubinate, respectively; phosphorus and sulfur suggest the presence of proteins in gallstones, and some proteins (such as mucin) can promote the formation of gallstones. Conclusions: The contents of metal and nonmetal elements in gallstones can accurately be detected using ICP-AES. The formation of different types of gallstones is closely related to the difference of these elements. This study is of great significance to reveal the cause of gallstones formation.
- © 2016, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Yue Zhang AU - Chongyu Zhang AU - Da Guo AU - Xiaojun Huang AU - Junfa Xue AU - Jianming Ouyang PY - 2016/07 DA - 2016/07 TI - Concentrations of Trace Elements in Different Types of Gallstones and Their Effects on Gallstone Formation BT - Proceedings of the 2016 International Conference on Biomedical and Biological Engineering PB - Atlantis Press SP - 331 EP - 336 SN - 2468-5747 UR - https://doi.org/10.2991/bbe-16.2016.51 DO - 10.2991/bbe-16.2016.51 ID - Zhang2016/07 ER -