Proceedings of the 2016 International Conference on Biomedical and Biological Engineering

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Concentrations of Trace Elements in Different Types of Gallstones and Their Effects on Gallstone Formation

Authors
Yue Zhang, Chongyu Zhang, Da Guo, Xiaojun Huang, Junfa Xue, Jianming Ouyang
Corresponding Author
Yue Zhang
Available Online July 2016.
DOI
10.2991/bbe-16.2016.51How to use a DOI?
Keywords
Gallstones, Trace Element, ICP-AES, Cholesterol, Bile Pigment.
Abstract

Purpose: To study the concentrations of trace metals and nonmetals elements in different types of gallstones (cholesterol-, pigment-, mixed- and calcium carbonate type) and to explore the formation mechanisms of gallstones. Method: Inductively coupled plasma emission spectrometer (ICP-AES) was used to determine the concentrations of calcium, manganese, magnesium, iron, copper, zinc, sulfur, and phosphorus. Results: Calcium, copper, sulfur and phosphorus play important roles in the formation of pigment stones. High concentrations of Cu2+ and Ca2+ ions can coordinate with bilirubin to form calcium bilirubinate and copper bilirubinate, respectively; phosphorus and sulfur suggest the presence of proteins in gallstones, and some proteins (such as mucin) can promote the formation of gallstones. Conclusions: The contents of metal and nonmetal elements in gallstones can accurately be detected using ICP-AES. The formation of different types of gallstones is closely related to the difference of these elements. This study is of great significance to reveal the cause of gallstones formation.

Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biomedical and Biological Engineering
Series
Advances in Biological Sciences Research
Publication Date
July 2016
ISBN
10.2991/bbe-16.2016.51
ISSN
2468-5747
DOI
10.2991/bbe-16.2016.51How to use a DOI?
Copyright
© 2016, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Yue Zhang
AU  - Chongyu Zhang
AU  - Da Guo
AU  - Xiaojun Huang
AU  - Junfa Xue
AU  - Jianming Ouyang
PY  - 2016/07
DA  - 2016/07
TI  - Concentrations of Trace Elements in Different Types of Gallstones and Their Effects on Gallstone Formation
BT  - Proceedings of the 2016 International Conference on Biomedical and Biological Engineering
PB  - Atlantis Press
SP  - 331
EP  - 336
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-16.2016.51
DO  - 10.2991/bbe-16.2016.51
ID  - Zhang2016/07
ER  -