Target Control Infusion (TCI) Computer-Assisted Pump and Bispectral Index (BIS ) Monitoring Sedation System in Elderly Patients during Endoscopic Retrograde Cholangiopancreateography (ERCP)

DOI

10.2991/bbe-16.2016.77How to use a DOI?

Keywords

Computer-assisted Pump, Bispectral Index (BIS), Target Control Infusion (TCI), Endoscopic Retrograde Cholangiopancreateography (ERCP), Propofol.

Abstract

Objectives: The aim of this study was to investigate the safety and efficacy of propofol sedation with a target-controlled infusion (TCI) computer-assisted pump and bispectral index (BIS) monitoring in elderly patients during endoscopic retrograde cholangiopancreateography (ERCP). Methods: Included were 150 consecutive EPCP procedures elderly patients under propofol sedation with a TCI system. Patients were divided into 3 groups: group A, age 50-70 years (n=50); group B, age71-80 years (n=50);group C, age >80 years (n=50). We compared the propofol dose and adverse events (hypotension and hypoxemia) during ERCP. Results: Older patients required a lower target concentration of propofol with higher age period: Median target concentration are respectively 2.6 g/mL,2.1 g/mL and 1.6 g/mL in the three groups. Hypotension tended to occur in the younger group, and hypoxemia occurred at a significantly higher rate in the older groups, although the number of cases was small. Low preoperative systolic blood pressure (<80 mm Hg) was associated with hypotension and abnormal pulmonary function was associated with hypoxemia in groups B and C. Conclusions: Elderly patients required lower doses of propofol with TCI/BIS system than younger patients. Attention to hypoxemia is necessary in elderly patients, particularly patients with abnormal pulmonary function.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Kai Li
AU  - Bin Zhang
AU  - Ying Zhang
AU  - Fang Wang
AU  - Chunmei Chu
PY  - 2016/07
DA  - 2016/07
TI  - Target Control Infusion (TCI) Computer-Assisted Pump and Bispectral Index (BIS ) Monitoring Sedation System in Elderly Patients during Endoscopic Retrograde Cholangiopancreateography (ERCP)
BT  - Proceedings of the 2016 International Conference on Biomedical and Biological Engineering
PB  - Atlantis Press
SP  - 494
EP  - 498
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-16.2016.77
DO  - 10.2991/bbe-16.2016.77
ID  - Li2016/07
ER  -