Proceedings of the 2016 International Conference on Biomedical and Biological Engineering

Target Control Infusion (TCI) Computer-Assisted Pump and Bispectral Index (BIS ) Monitoring Sedation System in Elderly Patients during Endoscopic Retrograde Cholangiopancreateography (ERCP)

Authors
Kai Li, Bin Zhang, Ying Zhang, Fang Wang, Chunmei Chu
Corresponding Author
Kai Li
Available Online July 2016.
DOI
https://doi.org/10.2991/bbe-16.2016.77How to use a DOI?
Keywords
Computer-assisted Pump, Bispectral Index (BIS), Target Control Infusion (TCI), Endoscopic Retrograde Cholangiopancreateography (ERCP), Propofol.
Abstract
Objectives: The aim of this study was to investigate the safety and efficacy of propofol sedation with a target-controlled infusion (TCI) computer-assisted pump and bispectral index (BIS) monitoring in elderly patients during endoscopic retrograde cholangiopancreateography (ERCP). Methods: Included were 150 consecutive EPCP procedures elderly patients under propofol sedation with a TCI system. Patients were divided into 3 groups: group A, age 50-70 years (n=50); group B, age71-80 years (n=50);group C, age >80 years (n=50). We compared the propofol dose and adverse events (hypotension and hypoxemia) during ERCP. Results: Older patients required a lower target concentration of propofol with higher age period: Median target concentration are respectively 2.6 g/mL,2.1 g/mL and 1.6 g/mL in the three groups. Hypotension tended to occur in the younger group, and hypoxemia occurred at a significantly higher rate in the older groups, although the number of cases was small. Low preoperative systolic blood pressure (<80 mm Hg) was associated with hypotension and abnormal pulmonary function was associated with hypoxemia in groups B and C. Conclusions: Elderly patients required lower doses of propofol with TCI/BIS system than younger patients. Attention to hypoxemia is necessary in elderly patients, particularly patients with abnormal pulmonary function.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Proceedings
International Conference on Biomedical and Biological Engineering
Part of series
Advances in Biological Sciences Research
Publication Date
July 2016
ISBN
978-94-6252-216-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bbe-16.2016.77How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Kai Li
AU  - Bin Zhang
AU  - Ying Zhang
AU  - Fang Wang
AU  - Chunmei Chu
PY  - 2016/07
DA  - 2016/07
TI  - Target Control Infusion (TCI) Computer-Assisted Pump and Bispectral Index (BIS ) Monitoring Sedation System in Elderly Patients during Endoscopic Retrograde Cholangiopancreateography (ERCP)
BT  - International Conference on Biomedical and Biological Engineering
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-16.2016.77
DO  - https://doi.org/10.2991/bbe-16.2016.77
ID  - Li2016/07
ER  -