A Novel Biphasic Scaffold with Gradient Pore Structures for Osteochondral Tissue Engineering
- https://doi.org/10.2991/bep-16.2017.2How to use a DOI?
- gradient scaffold; 3D printing
This study was aimed at using biomimetic strategies to construct a biphasic scaffold. Biphasic scaffolds were constructed using the 3-dimentional printing technology with two phases: the bony phase and the chondral phase. The bony phase was using the composition of poly (lactide-co-glycolide) (PLGA) and Polyethylene glycol PEG; the chondral phase was using hydrogel consisting of GelMA and hyaluronic acid. Also we designed a gradient pore size in the bony phase to better mimic the natural bone tissue. In vitro tests have shown the stratified scaffolds with gradient designs were effective for the multi-tissue formation.
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Duo PAN AU - Ruixue YIN AU - Hongbo ZHANG AU - Shengbing YANG AU - Wenjun ZHANG PY - 2016/12 DA - 2016/12 TI - A Novel Biphasic Scaffold with Gradient Pore Structures for Osteochondral Tissue Engineering BT - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016) PB - Atlantis Press SP - 6 EP - 10 SN - 2468-5747 UR - https://doi.org/10.2991/bep-16.2017.2 DO - https://doi.org/10.2991/bep-16.2017.2 ID - PAN2016/12 ER -