Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

A Novel Biphasic Scaffold with Gradient Pore Structures for Osteochondral Tissue Engineering

Authors
Duo PAN, Ruixue YIN, Hongbo ZHANG, Shengbing YANG, Wenjun ZHANG
Corresponding Author
Duo PAN
Available Online December 2016.
DOI
https://doi.org/10.2991/bep-16.2017.2How to use a DOI?
Keywords
gradient scaffold; 3D printing
Abstract

This study was aimed at using biomimetic strategies to construct a biphasic scaffold. Biphasic scaffolds were constructed using the 3-dimentional printing technology with two phases: the bony phase and the chondral phase. The bony phase was using the composition of poly (lactide-co-glycolide) (PLGA) and Polyethylene glycol PEG; the chondral phase was using hydrogel consisting of GelMA and hyaluronic acid. Also we designed a gradient pore size in the bony phase to better mimic the natural bone tissue. In vitro tests have shown the stratified scaffolds with gradient designs were effective for the multi-tissue formation.

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
Series
Advances in Biological Sciences Research
Publication Date
December 2016
ISBN
978-94-6252-287-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bep-16.2017.2How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Duo PAN
AU  - Ruixue YIN
AU  - Hongbo ZHANG
AU  - Shengbing YANG
AU  - Wenjun ZHANG
PY  - 2016/12
DA  - 2016/12
TI  - A Novel Biphasic Scaffold with Gradient Pore Structures for Osteochondral Tissue Engineering
BT  - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
PB  - Atlantis Press
SP  - 6
EP  - 10
SN  - 2468-5747
UR  - https://doi.org/10.2991/bep-16.2017.2
DO  - https://doi.org/10.2991/bep-16.2017.2
ID  - PAN2016/12
ER  -