Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

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91 articles

Effects of Total Flavonoids of Rosa Chinensis on Focal Cerebral Ischemia Reperfusion Model in Mice

Xiaoli YAN, Huisu WU, Xiaoyan FANG, Minsan MIAO
To observe the effects of total flavonoids of Rosa chinensis on focal cerebral ischemia reperfusion model in mice, Method: Nimodipine group, cerebral collaterals group, large, medium and small doses group of the Rosa chinensis total flavonoids were administered with corresponding drugs; Sham operation...

Research Status and Development Trend of The Signal Pathway of Allergic Asthma

Hexia LI, Chaopin LI, Xinfeng WANG, Qian LIU
Allergic asthma is a chronic airway inflammatory disease characterized by the infiltration of eosinophils in the lungs and the production of various kinds of stimulating factors, incidence rate showed an upward trend. In this paper, the research status and future development trend of the signal pathway...

Electrochemical Study on A Heme-Histidine-Sodium Decyl Sulfate Nano Micelles Complex Artificial Peroxidase

Di LI, Yushuai ZHANG, Fangyong GENG, Baolin XIAO, Jun HONG, Tao HONG
A heme-histidine-sodium decyl sulfate nano micelles complex with peroxidase activity (MAP) was constructed self-assembly and immobilized on a hydroxy fullerene modified glassy carbon electrode. The cyclic voltammograms of the modified electrode with a pair of redox peaks were investigated. The formal...

Microbial Production of Xylitol from D-arabitol by Gluconobacter Oxydans

Huanhuan ZHANG, Junhua YUN, Tinashe Archbold MAGOCHA, Miaomiao YANG, Yanbo XUE, Xianghui QI
Xylitol, a five carbon sugar alcohol, has numerous applications in the fields of food and pharmaceuticals. Gluconobacter oxydans contains two enzymes which are membrane-bound D-arabitol dehydrogenase and soluble xylitol dehydrogenase enabling the production of xylitol from D-arabitol. This review provides...

One New Monoterpenoid from the Fruit of Gardenia Jasminoides

Yueming ZUO, Zhongli ZHANG
One new monoterpenoid, 5-aldehyde-6'-O-sinapoyljasminoside A (1), together with two known compounds 6'-O-sinapoyljasminoside B(2) and 6'-O-trans-sinapoyljasminoside L(3), were isolated from the fruits of Gardenia jasminoides Ellis. The structures of the new monoterpenoid compound were elucidated by means...

Study on The Mildewproof Method of Fresh Xinhui Citrus Peels

Chen LI, Yingzhu WU, Jingyi MA, Leyu MA, Ning QING
To explore the effect to storage method of fresh Xinhui citrus peels by using against storage and ethanol mildewproof method, the main fungus which caused the mildew of fresh peels was also checked. The effect of hance ginger on peel moldy was observed by changing the humidity of storage environment...

Soil Respiration and Photosynthesis of Leaves in Greenhouse Cultivation Cherry Tomato

Yinli LIANG, Tianli BAO, Lan MU
To explore the optimum growth condition of cherry tomato (Lycopersiconesculentum), the cherry tomato was used to study the soil respiration and photosynthesis of leaves under greenhouse and outdoor condition with Lou soil and loessial soil during fruiting period in the year 2013 and 2014.The results...

Exploration of Chinese Ecological and Environmental Philosophy

Shaoyao HE, Duo LI, Ouyang DUO
Chinese traditional culture contains rich ecological philosophy thought. This paper focuses on the analysis of the ecological and environmental philosophy of "harmony between man and nature" in Chinese ancient Confucianism and Taoism. It is believed that the thought has important practical guiding function...

Increased Performance of Single-Chamber Air Cathode Microbial Fuel Cell Using Power Management System

Longsheng QIAO, Zhiwei XIAO, Ben'ai CHENG, Zhengyuan TAO, Zhichao HE, Jie WANG
Electricity generation by single-chamber air cathode fuel cells (MFCs) is considerably influenced by power management system(PMS). This study showed that application of PMS connected with a single-chamber air cathode MFC significantly improved its columbic efficiencies (CEs), current, and power output....

Animal Model Analysis based on the Characteristics of Clinical Symptoms of Alcoholic Hepatic Injury

Le KANG, Zhenya HU, Xiaoyan FANG, Mingsan MIAO
Objective: Based on the analysis of the characteristics of traditional Chinese medicine and Western medicine clinical symptoms of alcoholic liver injury. Method: In this paper, the characteristics and modeling methods of alcoholic liver injury animal model were summarized through analyzing the clinical...

The Influence of Climate Factor on the Yield of Winter Wheat in Germany based on LINTUL 2 Model

Zhe LIU, Ying HOU
The study, which was conducted in Klein-Altendorf, Nordrhein-Westfalen in Germany, simulated the effect of temperature and solar radiation on the yield of winter wheat from 1991 to 2004 by using LINTUL 2 model. The parameters of temperature and radiation were modified to check the sensitivity of the...

The effective part of Dioscorea nipponica Makino on esophageal carcinoma cells and the interaction with human serum albumin

Fuchun SI, Wenbin WANG
The effective part (BESDM) was extracted from the DioscoreaÿnipponicaÿMakino. Cytotoxicity of the BESDM on Ec9706, Eca109 and TE1 cells tested by MTT assay. The result showed the Ic50 values of Ec9706, Eca109 and TE1 are 7.87ñ0.08, 3.76ñ0.04 and 13.53ñ0.06 gúml-1, respectively. Fluorescence was used...

A Novel Biphasic Scaffold with Gradient Pore Structures for Osteochondral Tissue Engineering

Duo PAN, Ruixue YIN, Hongbo ZHANG, Shengbing YANG, Wenjun ZHANG
This study was aimed at using biomimetic strategies to construct a biphasic scaffold. Biphasic scaffolds were constructed using the 3-dimentional printing technology with two phases: the bony phase and the chondral phase. The bony phase was using the composition of poly (lactide-co-glycolide) (PLGA)...

Numerical and Physical Models of Distal Anastomosis in Coronary Artery Bypass Grafting

Haiyan LONG, Gang YANG
The progressive anastomotic intimal hyperplasia has been considered as a major failure reason for coronary artery bypass grafting (CABG), which is associated with the abnormality of the hemodynamic conditions. We designed a set of plexiglass models which can serve as in vitro cells or tissue culture...

Preliminary Study on The SYBR Green I RT- qPCR for Rabbit Hemorrhagic Disease Virus 2 (RHDV2) Detection

Zexiao YANG, Yadong LIU, Zhengqun MENG, Bo WANG, Xueping YAO, Yin WANG, Yi GENG, Yan LI
To develop a rapid method for the detection RHDV2, 4 specific primers and 12 overlapping PCR primers were designed to amplify the conserved RHDV2 specific DNA fragment according to the genome sequences of RHDV and RHDV2 published in GenBank. Based on the synthesis of a conserved part of the RHDV2 sequence...

Comparison of Biota Species Sensitivity Distributions to Nonylphenol in China and the United States

Liangmao ZHANG, Caidi WEI, Mingwei SONG
Based on the acute toxicity data for aquatic organisms from China and the United States, species sensitivity distributions (SSDs) were developed to derive to HC5 (the Hazardous Concentration for 5% of the species). Sensitivity to NP in taxa of vertebrates, invertebrates and plants were compared separately...

Porous In2O3 Nanorods: Synthesis and Enhanced NOx Gas-Sensing Properties at Room Temperature

Wenyi LIU, Wencheng FANG, Shuai ZHANG, Guizhi LIU, Yue SUN, Cheng WANG, Chengxin ZHANG, Na GAN, Ying YANG
A novel room temperature gas sensor based on porous In2O3 nanorods was successfully synthesized via a facile reflux method. The In2O3 demonstrates a rod-like shape with a diameter of 10 - 20 nm and a length about 70 - 100 nm, which displays good and uniform size. Studies have shown that the porous In2O3...

Bactericidal Activity and Physiological Effects of Combined Application of Poly-Hexamethylene Biguanide Hydrochloride and 1-bromo-3-chloro-5, 5-dimethylimidazolidine-2, 4-dione on Staphylococcus aureus

Wan HUAI, Zhirui DENG, Qin CHEN
Poly-hexamethylene biguanide hydrochloride (PHMB) and 1-bromo-3- chloro-5,5-dimethylimidazolidine-2,4-dione (BCDMH) are widely used for surface disinfection. Here, we examined the bactericidal effects of the mixture of PHMB and BCDMH (named PB) combined in different ratios on S. aureus, and studied effects...

Research on Refining Gold from Electronic Waste

Xia HUO, Ronghua LU, Mingzhe HU, Yue YIN
Due to the fast development of electronic waste and the gradually deficient of the modern resources, the environment is deteriorated seriously. Thus, the recycling and utilizing of electronic waste becomes an important research area in modern scientists. In the present paper, the authors employ H2SO4...

Urban Ecological Environmental Standards based on Subjective Evaluations of Various Environments

Lei YU, Dongchao XU, Hong LIANG, Jia'nan HOU
With fast urbanization, urban nature environment has been largely damaged. A primary ecological system is being destroyed. In order to a sustainable development, environmental standards for maintain an ecological system for a city have to be established. This study demonstrates a new approach for establishing...

A Study on the Environmental Education and Compulsory Education Equalization Issue-A case study of Shandong Province

Xili YANG
Environmental education is a type of education activity which takes the relationship between human beings and the environment as the core. This article takes Shandong province as an example to carry out environmental education and compulsory education equalization issue research, combine environmental...

Preparation and Characterization of a Novel Absorber for Formaldehyde

Tianhui HUANG, Hong LIU, Yuan XI, Yan LIU, Gang ZHOU
Formaldehyde is one of the substances causing sick for human being.Small doses of formaldehyde can cause a variety of symptoms of physical discomfort. High dose and long time exposure to formaldehyde will increase the probability of cancer. However, the content of formaldehyde in the newly renovated...

Review on Rainfed Agriculture and Rainwater Harvesting Techniques

Ziye LIU, Junying JIN
This paper summarizes the importance of water resource and more and more serious situations facing agricultural water use. Rainfed agriculture is a necessary way for crop production and food security. As one of the most efficient tool, rainwater harvesting can supplement rainfed agricultural and hence...

Lampblack Pollution and Control Measures in the Canteen of a University in Ji'nan

Ting LI, Xupeng WEI
The environment is usually changed to benefit human life. However, advances come with a significant environment cost. Our health is suffering severe persecution that created by burning fossil fuels and pour polluting chemical waste into the living environment. Canteen is an important place for college...

Study on the Characteristic of Adsorption Kinetics of Organochlorine Pesticides in Agricultural Soils

Ming GAO, Xuming SUN, Hui HUANG
To study the characteristic of adsorption kinetics of BHC and DDT in the unsaturated zone of typical northeastern soil field of China by adopting indoor soil adsorption simulation experiment. The purpose of the study is to reveal the pollution mechanism of BHC and DDT to soil and groundwater and provide...

Preparation and Photocatalytic Properties of TiO2 Immobilized on Fiberglass Cloth

Yiqun CHEN, Deqiang CHEN, Zhaoping WEI, Yang CHEN
In this study, the TiO2 immobilized on fiberglass cloth was prepared to improve the photocatalytic activity of TiO2 and overcome the difficulty of reuse through a set of different procedures. The microstructure and morphology of TiO2 loaded on FGC were characterized via SEM and XRD, respectively. The...

ITS and Trnl-F Sequences Analysis of Pulsatilla.Dahurica (Fisch.) Spr.

Tiantian WANG, Guanzhun LIN, Shaoxuan ZHANG, Yarong LI
To provide scientific data of the internal transcribed spacer (ITS) and trnL-F sequences for the authentication of Pulsatilla chinesis (Bge.) Regel., we extracted the genome DNA from the leaves of Pulsatilla.dahurica (Fisch.) Spr., collected in Jilin Province, amplified the ITS and trnL-F region using...

Preliminary Study on The RT-LAMP Assay for Rabbit Hemorrhagic Disease Virus Type 2 Detection

Zexiao YANG, Yilin LUO, Zhengqun MENG, Xueping YAO, Han ZHANG, Yin WANG, Xiaoxue XIANG, Lijun ZHOU, Yadong LIU, Yan LI
To develop a rapid molecular biological method for the detection of rabbit hemorrhagic disease virus type 2 (RHDV2), a set of 4 primers were designed according to the conserved sequence fragment of the capsid protein(VP60) gene of RHDV2 published in GenBank, and the reverse transcriptase loop-mediated...

The Microbial Community in A Chinese Traditional Fermented Suanrou by High Throughput Sequencing

Ping HU, Yun CHEN, Jianlong ZHAN, Yulong ZHANG
Microbial diversity in a Chinese traditional spontaneous fermented sour meat product, Suanrou, was investigated using High-throughput sequencing. A taxonomic analysis was carried out on 1248 OTUs obtained with 454-pyrosequencing of 16S rRNA amplicons of the bacterial microbiota in 3samples of suanrou...

Research and Implementation of Discovering and Recommending Experts in Medical Community-Based Q&A

Lan FANG, Yu FANG
With the continuous development of the Internet, community-based Q&A (CQA) system has become an effective platform for people to access online information and help. People can submit their own question in CQA and get answers from others. There will be an enormous amount of questions all the time, and...

Progress in Research on Small Molecules as Gene-targeted Drugs

Yanli WANG, Sijia WANG, Jun XU, Wen ZHANG
The findings of effective targets and the identification of target binding molecules are two key points in drug discovery. The complete human genome and their rapid increase in structural and functional information led to new possibilities for diagnosis and therapy of diseases, using gene-targeted drugs....

Blends of Poly (L-Lactic Acid) and Glucose Prepared from Mixture Solution

Dan CAO, Qinwei GAO, Yinping ZHAO, Wei MING
Poly (L-lactic acid) (PLLA) and glucose (Glu) were respectively dissolved in N, N-dimethyl acetamide to prepare solutions. The blends of PLLA and glucose with various ratios were prepared by mixed solution method, and characterized with infrared Fourier transform spectrometry, differential scanning calorimetry,...

Evaluation of the Karst Water Quality Upstream of Junhe River Basin in Shandong Province, China

Mingyi REN, Liyuan YANG, Jiezhong WANG, Chunhua LIU
Seventy nine karst water samples were used to study the quality of groundwater in upstream of Junhe River. The main hydrochemical types were HCO3 type, HCO3⋅SO4 type, HCO3⋅Cl type and Cl type, and the HCO3 type occupied 58% of the total evaluation area. The sample points were grouped in the lower-left...

A Novel Feature Selection Method for Gene Expression Data Based on Samples Localization

Mingyue SHENG, Wei DU, Yuan TIAN, Yanchun LIANG
It is an important and hot topic for researchers to develop an efficient and robust feature selection method from gene expression profile data with thousands of genes and small sample size. At present, most of feature selection methods are constructed models to use all samples of gene expression data,...

Effect of Compound-Maqin-Decoction on P38MAPK and Foxp3 Protein Expression of Lung Issue in Asthmatic Rats

Peng QIAN, Zhaoxia XU, Xueping LI, Sijing WANG
OBJECTIVE: To observe the effect of Compound-Maqin-Decoction (CMD) on p38MAPK and Foxp3protein expression of lung issue in asthmatic rats. METHODS: The asthmatic rat model was established by ovalbumin and was intervened with CMD. After inducing asthma and four-week treatment, the rats were sacrificed...

A Method for Blink Artifact Detection and Removal with Wavelet Transform and Hilbert Transform

Xiaobai CAI, Junjun CHEN
This paper presents a method of blink artifact removal of single lead EEG signal. After a wavelet transform signal singularity points are detected and modulus maxima values of wavelet transform are applied to find peaks of blink artifacts. By using Hilbert transform instantaneous frequency is obtained....

The Synthesis of Diazinon with The Catalysis of Ionic Liquid under The Condition of Microwave

Lin HU, Yegui WANG, Xiaoqin ZHOU, Juan TANG, Jingqing LI, Kuijiang WONG, Wenyuan XU
A novel synthetic methods for the efficient and environmentally-friendly production will provide useful inspiration. This report presents a novel method for microwave-assisted synthesis of diazinon with different organic solvents, microwave heating power, heating time, catalysts. The optimal conditions...

N-Glycosylation Sited at Residues of Catalytic Center Could Repress The Activity of Endoglucanase from Rhizopus Stolonifer

Bin TANG, Yingying ZHANG, Wei CHENG, Qingqing ZHANG, Song LI
As a common post-translational modification of proteins, glycosylation has been proven effectively influence the activity of enzyme. To improve the activity of endoglucanase (EGII) from Rhizopus stolonifer TP-02, we studied the effect of glycosylation on the structure and activity of EGII. Two potential...

Three Monoterpenoids Eucommiol from The Leaves of Eucommia Ulmoides Protect against Neurotoxicity in PC12 Cells

Yueming ZUO, Zhongli ZHANG
One new monoterpenoid compound 4'-acetyl-eucommiol (1) and two known compounds eucommiol(2), 1-deoxyeucommiol(3) were isolated from the leaves of Eucommia ulmoides. The structures of the new monoterpenoid eucommiol were elucidated by means of chemical evidence and 1D-and 2D-NMR (1H, 13C, HSQC, HMBC,...

The Phase of Oscillation in Cortical Network and Its Relationship with Firing Rate and Neuronal Activation

Daming WANG, Yaoru SUN
Gamma-band neuronal oscillation and synchronization (30-90 Hz) are frequently observed in several cortical and subcortical circuits and are supposed to be involved in a variety of cognitive functions. The phase of the oscillation, referred to as one aspect of communication through coherence (CTC) hypothesis,...

Prognostic Analysis of The Effects of Starvation and Overfeeding on Children

Le KANG, Mingsan MIAO
By comparing the effects of excess nutrients and malnutrition on the body of children, It is concluded that the harm to children's body caused by excessive nutrition is more than that of malnutrition, and overnutrition is also a performance of malnutrition. The causes of obesity in children, the present...

A Recurrence Quantification Analysis of Traditional Chinese Medicine Pulse and Its Application in Assessment of Coronary Artery Disease

Rui GUO, Yiqin WANG, Jianjun YAN, Haixia YAN
Purpose: This study was conducted to illustrate that pulse diagnosis of traditional Chinese medicine (TCM) was useful in the assessment of coronary artery lesions in patients with Coronary Heart Disease (CHD). Methods: By using phase-space reconstruction, one-dimensional pulse signals of participants...

Melittin: A Key Composition of Honey Bee Venom with Diverse Pharmaceutical Function

Sheng HUANG, Jianhua WANG, Xiaozhong WANG, Chenghong LI
Melittin is the main toxic component in the the honey bee venom. It is a cationic, lytic peptide constituted by 26 amino acid residues. This peptide is an amphoteric molecule which the carboxy-terminal region is hydrophilic and the amino-terminal region is hydrophobic due to the presence of a series...

Crystallization of the Racemic Conglomerate and Racemic Compound of Efonidipine

Linyuan ZHU, Zhanjun LI, Yuzhen YU, Wen LI
Efonidipine is a dual blocker of T-type and L-type calcium channels with 1, 4-dihydropyridine structure attached to a phosphonate skeleton. As a chiral compound, it has a special property that can exist as a racemic conglomerate or a racemic compound based on the different crystallization conditions....

Cooking Fumes and Relative Diseases

Chunyan WANG, Lifang LIU, Guoping HE
Cooking fumes are mixture of various toxic components such as aldehydes, heterocyclic amines (HCAs), polycyclic aromatic hydrocarbons (PAHs), fat aerosols and particulate matters (PM), which are mainly produced during or after cooking. Due to the toxic contents of CFs, CFs might cause lung toxicity,...

A Review of the Research on the Measurement Methods of Greenhouse Gas Emission Reduction for LNG Automotive Applications

Dongxiang CHENG, Fanghua ZHAO, Jing CHEN
With the rapid development of economy in China, the demand of the society to the transportation industry is also increasing [1]. This has produced a large number of car greenhouse gas, causing serious damage to the environment. As a new development of clean energy industry, liquefied natural gas (LNG)...

Effects of Propranolol on Osteoclasts Cultured in Vitro

Xiaojuan LI, Xiaorui XIE, Jin REN, Liling REN, Jian CAO
Objective: To study the effect of propranolol on osteoclasts. Methods: (1)propranolol at the doses of 10-2 µmol/ml, 10-3 µmol/ml, 10-4 µmol/ml, were added into the osteoclasts for coculture for 72 h, then tartrate-resistant acid phosphatase (TRAP) and toluidine blue staining...

Synthesis and Performance of A Novel Penetration Enhancer

Qin WU, Lei TANG, Haimin SHEN, Hongxin SHI
Preparation and percutaneous absorption of 2-methyl-2-perfluoro-2'-methyl-3'-oxoca- proyloxyl ethoxycarbonyl ethylmethyldipolyethoxylsilicane (V) were investigated. V was synthesized from 2-perfluoro-2'-methyl-3'-oxocaproyloxylethyl methacrylate and methyldichlorosilicane by hydrosilication, then by...

Enhancement of The Edible Mushroom Pleurotus Ostreatus Yield via A New Liquid Fermentation Tank

Xiaoyu DUAN, Yu HU, Yuxian YOU, Qianqian TANG, Yiwen LI, Lan ZHANG, Cheng LI, Yuntao LIU
Nowadays, the edible and medicinal values of edible fungi have been widely recognized all over the world, particularly in China and Japan, the edible fungi have become important ingredients in Traditional Chinese Medicine. Hundreds of species of edible fungi had been studied and confirmed with biological...

Study on Adsorption Capacities of Heavy Metals in Biofilms Grown on Magnetic Carriers

Zhaoxu LI, Fang YANG, Ran JIANG, Liqiang XU
The adsorption capacities of heavy metals in biofilms have the potential advantage of high efficiency. More and more attention has been paid to the study of the adsorption of heavy metals in biofilms. This study designed four reactors to test the adsorption capacities of heavy metals in biofilms grown...