Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

Melittin: A Key Composition of Honey Bee Venom with Diverse Pharmaceutical Function

Authors
Sheng HUANG, Jianhua WANG, Xiaozhong WANG, Chenghong LI
Corresponding Author
Sheng HUANG
Available Online December 2016.
DOI
https://doi.org/10.2991/bep-16.2017.40How to use a DOI?
Keywords
melittin; active mechanism; anticancer; anti-viral; medical function
Abstract

Melittin is the main toxic component in the the honey bee venom. It is a cationic, lytic peptide constituted by 26 amino acid residues. This peptide is an amphoteric molecule which the carboxy-terminal region is hydrophilic and the amino-terminal region is hydrophobic due to the presence of a series of positively charged amino acids. Melittin shows the interaction with biological membrane or enzyme to amphiphilic property. Based on these properties, melittin is an important candidate use for antibiotic-resistant bacteria, cancer and tumor and pathogenicity virus treatment. This review introduces the possible active mechanism of melittin and recent research progress in medical.

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
Series
Advances in Biological Sciences Research
Publication Date
December 2016
ISBN
978-94-6252-287-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bep-16.2017.40How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Sheng HUANG
AU  - Jianhua WANG
AU  - Xiaozhong WANG
AU  - Chenghong LI
PY  - 2016/12
DA  - 2016/12
TI  - Melittin: A Key Composition of Honey Bee Venom with Diverse Pharmaceutical Function
BT  - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
PB  - Atlantis Press
SP  - 193
EP  - 197
SN  - 2468-5747
UR  - https://doi.org/10.2991/bep-16.2017.40
DO  - https://doi.org/10.2991/bep-16.2017.40
ID  - HUANG2016/12
ER  -