Melittin: A Key Composition of Honey Bee Venom with Diverse Pharmaceutical Function
- https://doi.org/10.2991/bep-16.2017.40How to use a DOI?
- melittin; active mechanism; anticancer; anti-viral; medical function
Melittin is the main toxic component in the the honey bee venom. It is a cationic, lytic peptide constituted by 26 amino acid residues. This peptide is an amphoteric molecule which the carboxy-terminal region is hydrophilic and the amino-terminal region is hydrophobic due to the presence of a series of positively charged amino acids. Melittin shows the interaction with biological membrane or enzyme to amphiphilic property. Based on these properties, melittin is an important candidate use for antibiotic-resistant bacteria, cancer and tumor and pathogenicity virus treatment. This review introduces the possible active mechanism of melittin and recent research progress in medical.
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Sheng HUANG AU - Jianhua WANG AU - Xiaozhong WANG AU - Chenghong LI PY - 2016/12 DA - 2016/12 TI - Melittin: A Key Composition of Honey Bee Venom with Diverse Pharmaceutical Function BT - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016) PB - Atlantis Press SP - 193 EP - 197 SN - 2468-5747 UR - https://doi.org/10.2991/bep-16.2017.40 DO - https://doi.org/10.2991/bep-16.2017.40 ID - HUANG2016/12 ER -