Synthesis of Dinucleoside Triphosphates Containing Antiviral Nucleoside
- https://doi.org/10.2991/bep-16.2017.45How to use a DOI?
- Zidovudine; Stavudine; Dinucleoside triphosphate; Antiviral nucleoside; Phosphoropiperidate.
A general and efficient method for the synthesis of asymmetrical dinucleoside triphosphates with an antiviral nucleoside moiety has been developed. The coupling of adenosine diphosphate with antiviral nucleoside phosphoropiperidate via the DCI activation of P-N bond afforded the desired products in good yield.
- © 2017, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Rong LIU AU - Shanshan GONG PY - 2016/12 DA - 2016/12 TI - Synthesis of Dinucleoside Triphosphates Containing Antiviral Nucleoside BT - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016) PB - Atlantis Press SP - 215 EP - 217 SN - 2468-5747 UR - https://doi.org/10.2991/bep-16.2017.45 DO - https://doi.org/10.2991/bep-16.2017.45 ID - LIU2016/12 ER -