Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

Synthesis of Dinucleoside Triphosphates Containing Antiviral Nucleoside

Authors
Rong LIU, Shanshan GONG
Corresponding Author
Rong LIU
Available Online December 2016.
DOI
https://doi.org/10.2991/bep-16.2017.45How to use a DOI?
Keywords
Zidovudine; Stavudine; Dinucleoside triphosphate; Antiviral nucleoside; Phosphoropiperidate.
Abstract

A general and efficient method for the synthesis of asymmetrical dinucleoside triphosphates with an antiviral nucleoside moiety has been developed. The coupling of adenosine diphosphate with antiviral nucleoside phosphoropiperidate via the DCI activation of P-N bond afforded the desired products in good yield.

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
Series
Advances in Biological Sciences Research
Publication Date
December 2016
ISBN
978-94-6252-287-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bep-16.2017.45How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Rong LIU
AU  - Shanshan GONG
PY  - 2016/12
DA  - 2016/12
TI  - Synthesis of Dinucleoside Triphosphates Containing Antiviral Nucleoside
BT  - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
PB  - Atlantis Press
SP  - 215
EP  - 217
SN  - 2468-5747
UR  - https://doi.org/10.2991/bep-16.2017.45
DO  - https://doi.org/10.2991/bep-16.2017.45
ID  - LIU2016/12
ER  -