Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

Effects of Propranolol on Osteoclasts Cultured in Vitro

Authors
Xiaojuan LI, Xiaorui XIE, Jin REN, Liling REN, Jian CAO
Corresponding Author
Xiaojuan LI
Available Online December 2016.
DOI
https://doi.org/10.2991/bep-16.2017.6How to use a DOI?
Keywords
propranolol ,osteoclasts. ,TRAP
Abstract

Objective: To study the effect of propranolol on osteoclasts. Methods: (1)propranolol at the doses of 10-2 µmol/ml, 10-3 µmol/ml, 10-4 µmol/ml, were added into the osteoclasts for coculture for 72 h, then tartrate-resistant acid phosphatase (TRAP) and toluidine blue staining was used to detect the effects of propranolol on osteoclasts. Results: compared with the control group, 10-2 µmol/ml, 10-3 µmol/ml, 10-4 µmol/ml group of propranolol were able to make the number of osteoclasts and bone resorption area decreased (P < 0.05) Conclusion different concentrations of propranolol can inhibit osteoclast bone resorption(P < 0.05).

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
Series
Advances in Biological Sciences Research
Publication Date
December 2016
ISBN
978-94-6252-287-9
ISSN
2468-5747
DOI
https://doi.org/10.2991/bep-16.2017.6How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Xiaojuan LI
AU  - Xiaorui XIE
AU  - Jin REN
AU  - Liling REN
AU  - Jian CAO
PY  - 2016/12
DA  - 2016/12
TI  - Effects of Propranolol on Osteoclasts Cultured in Vitro
BT  - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
PB  - Atlantis Press
SP  - 27
EP  - 29
SN  - 2468-5747
UR  - https://doi.org/10.2991/bep-16.2017.6
DO  - https://doi.org/10.2991/bep-16.2017.6
ID  - LI2016/12
ER  -