Effects of Propranolol on Osteoclasts Cultured in Vitro
- https://doi.org/10.2991/bep-16.2017.6How to use a DOI?
- propranolol ,osteoclasts. ,TRAP
Objective: To study the effect of propranolol on osteoclasts. Methods: (1)propranolol at the doses of 10-2 µmol/ml, 10-3 µmol/ml, 10-4 µmol/ml, were added into the osteoclasts for coculture for 72 h, then tartrate-resistant acid phosphatase (TRAP) and toluidine blue staining was used to detect the effects of propranolol on osteoclasts. Results: compared with the control group, 10-2 µmol/ml, 10-3 µmol/ml, 10-4 µmol/ml group of propranolol were able to make the number of osteoclasts and bone resorption area decreased (P < 0.05) Conclusion different concentrations of propranolol can inhibit osteoclast bone resorption(P < 0.05).
- © 2017, the Authors. Published by Atlantis Press.
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Cite this article
TY - CONF AU - Xiaojuan LI AU - Xiaorui XIE AU - Jin REN AU - Liling REN AU - Jian CAO PY - 2016/12 DA - 2016/12 TI - Effects of Propranolol on Osteoclasts Cultured in Vitro BT - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016) PB - Atlantis Press SP - 27 EP - 29 SN - 2468-5747 UR - https://doi.org/10.2991/bep-16.2017.6 DO - https://doi.org/10.2991/bep-16.2017.6 ID - LI2016/12 ER -