Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)

Progress in Research on Small Molecules as Gene-targeted Drugs

Authors
Yanli WANG, Sijia WANG, Jun XU, Wen ZHANG
Corresponding Author
Yanli WANG
Available Online December 2016.
DOI
10.2991/bep-16.2017.38How to use a DOI?
Keywords
gene-targeted drug; G-quadruplex; polyamide
Abstract

The findings of effective targets and the identification of target binding molecules are two key points in drug discovery. The complete human genome and their rapid increase in structural and functional information led to new possibilities for diagnosis and therapy of diseases, using gene-targeted drugs. Currently, gene-targeted drugs includes groove binders, intercalators, alkylators and cleavage agents and are widely used in cancer, Alzheimer's disease, blood pressure, heart and autoimmune diseases research and therapy. A review on the targeted genes, their interaction molecules and the application on disease therapy is presented.

Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Download article (PDF)

Volume Title
Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
Series
Advances in Biological Sciences Research
Publication Date
December 2016
ISBN
978-94-6252-287-9
ISSN
2468-5747
DOI
10.2991/bep-16.2017.38How to use a DOI?
Copyright
© 2017, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - CONF
AU  - Yanli WANG
AU  - Sijia WANG
AU  - Jun XU
AU  - Wen ZHANG
PY  - 2016/12
DA  - 2016/12
TI  - Progress in Research on Small Molecules as Gene-targeted Drugs
BT  - Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016)
PB  - Atlantis Press
SP  - 182
EP  - 186
SN  - 2468-5747
UR  - https://doi.org/10.2991/bep-16.2017.38
DO  - 10.2991/bep-16.2017.38
ID  - WANG2016/12
ER  -