Proceedings of the 2nd Borobudur International Symposium on Science and Technology (BIS-STE 2020)

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Extraction and Formulation of Quersetin Nanoemulation from Kenikir Leaves (Cosmos Caudatus Kunt) in the Phase of RBO Oil as Antioxidant

Authors
Siti Hajir, Ratri Ariatmi Nugrahani, Ismiyati, Nurul Hidayati Fithriyah
Corresponding Author
Ratri Ariatmi Nugrahani
Available Online 11 August 2021.
DOI
10.2991/aer.k.210810.088How to use a DOI?
Keywords
Kenikir (Cosmos Caudatus Kunth), Nanoemulsion, Quercetin, RBO (Rice Bran Oil), Antioxidant
Abstract

This study was an effort to obtain high yield of quercetin extraction from kenikir leaves employing several extraction methods, which were maceration, percolation, soxhlet, and reflux, using methanol as solvent followed by quercetin incorporation into a Nanoemulsion system with Rice bran oil (RBO) as the oil phase. The resulting Nanoemulsion was tested with antioxidant activity analyses using DPPH (1,1-diphenyl-2-picrylhydrazil) reagent. The nanoemulsion preparation was produced from kenikir leaf powder at 20% concentration. The characterizations of formula consisted of organoleptic tests, analyses of pH, particle size, emulsion type, and determination of quercetin content absorbed in the nanoemulsion system, as well as antioxidant activity testing. The results showed that the highest quercetin yield of 14.26 ppm was produced from the soxhlet method for two hours. The Nanoemulsion preparation with 20% kenikir leaf extract and RBO oil phase was good and stable. The formulations also exhibited 6.3 pH, O/W emulsion type, and 176.8 nm particle size. The absorption of quercetin in the nanoemulsion showed an %EE value of 99.99%, indicating the formulation’s high capacity to absorb quercetin. The antioxidant activity testing using DPPH assay produced an IC50 value of 106.805 ppm.

Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the 2nd Borobudur International Symposium on Science and Technology (BIS-STE 2020)
Series
Advances in Engineering Research
Publication Date
11 August 2021
ISBN
10.2991/aer.k.210810.088
ISSN
2352-5401
DOI
10.2991/aer.k.210810.088How to use a DOI?
Copyright
© 2021, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - Siti Hajir
AU  - Ratri Ariatmi Nugrahani
AU  - Ismiyati
AU  - Nurul Hidayati Fithriyah
PY  - 2021
DA  - 2021/08/11
TI  - Extraction and Formulation of Quersetin Nanoemulation from Kenikir Leaves (Cosmos Caudatus Kunt) in the Phase of RBO Oil as Antioxidant
BT  - Proceedings of the 2nd Borobudur International Symposium on Science and Technology (BIS-STE 2020)
PB  - Atlantis Press
SP  - 512
EP  - 518
SN  - 2352-5401
UR  - https://doi.org/10.2991/aer.k.210810.088
DO  - 10.2991/aer.k.210810.088
ID  - Hajir2021
ER  -