Proceedings of the 2016 International Conference on Biological Sciences and Technology

Novel Mercaptan Derivatives Nanogold Particles with Hyperchromic and Fluorescence Sensitization Effects

Authors
Dorothy Araba Yakoba Agyapong, Ran-Lin Zhao, Cai-Xia Li, Wen-Ju Du, Hong-Juan Zeng
Corresponding Author
Dorothy Araba Yakoba Agyapong
Available Online January 2016.
DOI
https://doi.org/10.2991/bst-16.2016.22How to use a DOI?
Keywords
Mercaptan derivatives nanogold particles, Carcinoembryonic antigen, Hyperchromic effect, Fluorescence sensitization effect.
Abstract
Carcinoembryonic antigen (CEA), typically associated with certain tumors is widely used as clinical tumor markers for diagnosing certain cancers and hence its detection is of great essence in clinical diagnostics. A large number of surface atoms of nanoparticles have huge surplus bonding ability, because of the surface effect of gold nanoparticles, resulting in reuniting and sinking among the nanoparticles which makes them unstable. However, for effective and efficient bioassay, a stable nanomaterial with good hyperchromic and fluorescence sensitization effects is of essence. In order to detect traces of CEA, a new kind of nanomaterial with hyperchromic and fluorescence sensitization effects is considered essential. In this paper, a new kind of mercaptan derivatives nanogold (MDN) particles is studied using ultraviolet-visible absorption spectra (UV-vis), fluorescence emission spectrum method. The prepared nanogold and MDN, was interacted with carcinoembryonic antigen (CEA). It was observed that the interaction between MDN and CEA had good hyperchromic and fluorescence sensitization effects. Given its promising advantage, it is expected that this nanomaterial with hyperchromic and fluorescence sensitization effects will be an attractive tool for use in many different elds.
Open Access
This is an open access article distributed under the CC BY-NC license.

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Proceedings
The International Conference on Biological Sciences and Technology
Part of series
Advances in Biological Sciences Research
Publication Date
January 2016
ISBN
978-94-6252-161-2
ISSN
2468-5747
DOI
https://doi.org/10.2991/bst-16.2016.22How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - CONF
AU  - Dorothy Araba Yakoba Agyapong
AU  - Ran-Lin Zhao
AU  - Cai-Xia Li
AU  - Wen-Ju Du
AU  - Hong-Juan Zeng
PY  - 2016/01
DA  - 2016/01
TI  - Novel Mercaptan Derivatives Nanogold Particles with Hyperchromic and Fluorescence Sensitization Effects
BT  - The International Conference on Biological Sciences and Technology
PB  - Atlantis Press
SN  - 2468-5747
UR  - https://doi.org/10.2991/bst-16.2016.22
DO  - https://doi.org/10.2991/bst-16.2016.22
ID  - Agyapong2016/01
ER  -