Analgesic Activity of Infusion of Beluntas Radix (Pluchea indica (L.)) on the Male Mice
- 10.2991/ahsr.k.200523.062How to use a DOI?
- radix, Pluchea indica L, infusion, analgesic, writhing method
Objectives: The study aims to determine the analgesic activity of beluntas radix infusion. Method: The research used 25 of male mice. The mice were divided into five groups, which are negative control, positive control, and three testing groups (in different doses). Fifteen minutes after infusion of beluntas radix per oral, the mice were given the acetic acid 0.7% i.p. The cumulative writhe was calculated in every 5 minutes for one hour and was counted for the protection and the effectivity percentage. Results and Discussions: Beluntas radix infusion of doses 9.75 mg/20 g, 19.5 mg/20 g and 29.25 mg/20 g of body weight decreased the writhing responses significantly (p<0.05) compared with the control. Each doses gave the protection percentage 55.8%, 64.2% and 77.5% and the effectivity percentage 113.4%, 130.5% and 157.5%. Conclusion: Analgesic activity of beluntas radix infusion is influenced by dose level. Test dose III (29.25 mg / 20 g BW of mice) has the best activity.
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Cite this article
TY - CONF AU - Hendy Suhendy AU - Muharam Priatna AU - Yoppi Iskandar PY - 2020 DA - 2020/06/08 TI - Analgesic Activity of Infusion of Beluntas Radix (Pluchea indica (L.)) on the Male Mice BT - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019) PB - Atlantis Press SP - 258 EP - 260 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.200523.062 DO - 10.2991/ahsr.k.200523.062 ID - Suhendy2020 ER -