Ethanol Extract Activity of Yellow Pumpkin Flesh (Cucurbita Moschata Duch) on the Cataract Formation
- https://doi.org/10.2991/ahsr.k.200523.029How to use a DOI?
- cataract, Cucurbita moschata Duch, sodium selenit
Objectives Oxidative stress is suspected as a major factor triggering cataracts. Yellow pumpkin contains beta-carotene compounds can reducing oxidative stress, and it is suspected to be able to reduce the occurrence of cataracts. This study aims at determining and proving the benefits of yellow pumpkin (Cucurbita moschata Duch) as a deterrent in cataract formation in male albino rats (Wistar strain) induced by Sodium Selenite. Macroscopic and microscopic features of cataract formation on negative controls included in mature cataracts (stadium 3), at the dose I and dose III including incipient cataracts (stadium 2) and dose II including immature cataracts (stadium 1). The average parameter diameter of the lens (μm) of group dose II (1738 ± 583) and dose III (1825 ± 106) experiences a widening of the lens diameter compared to the negative control (1492 ± 52). Whereas, at the dose I (1392 ± 38), there was a narrowing compared to the negative control. The parameters of lens epithelial cell thickness (μm) at dose I (15 ± 3.46), dose II (15.67 ± 5.03), and dose III (9.67 ± 4.62) of ethanol extract of yellow pumpkin showed an increase in thickness lens epithelial cells of mouse compared to negative controls (7 ± 1). The ethanol extract of the flesh of yellow pumpkin showed the improvement of eye health of albino rats (Wistar strain) experienced cataract, although it has not been able to improve it on the whole.
- © 2020, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Tita Nofianti AU - Nurlaili Dwi Hidayati AU - Vera Nurviana AU - Ruswanto AU - L Rani Yunda PY - 2020 DA - 2020/06/08 TI - Ethanol Extract Activity of Yellow Pumpkin Flesh (Cucurbita Moschata Duch) on the Cataract Formation BT - The proceedings of the 2nd Bakti Tunas Husada-Health Science International Conference (BTH-HSIC 2019) PB - Atlantis Press SP - 118 EP - 123 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.200523.029 DO - https://doi.org/10.2991/ahsr.k.200523.029 ID - Nofianti2020 ER -