Proceedings of the International Conference on Chemical, Material and Food Engineering

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The Effects of Flavonoids from Eucommia Ulmoides on Body's Antioxidant Systems, Lipid Peroxidation and Oxidative DNA Damage after Exhaustive Exercise

Authors
JinYang Lin, ZhuoYing Zhang
Corresponding Author
JinYang Lin
Available Online July 2015.
DOI
10.2991/cmfe-15.2015.5How to use a DOI?
Keywords
flavonoids from Eucommia ulmoides; reduced glutathione; oxidized glutathione; superoxide dismutase; catalase; malondialdehyde; 8-hydroxy-2'-deoxyguanosine
Abstract

Objective: this study examined the effects of flavonoids from Eucommia ulmoides (FEU) on antioxidant systems, lipid peroxidation and oxidative deoxyribonucleic acid (DNA) damage after exhaustive exercise. Methods: the mice were then divided into four groups, one control group and three FEU treated groups. The control group received saline solution, whilst the treated groups received different doses of FEU (5, 15 and 45 mg/kg BW) for 28 days, followed by being forced to undergo swimming test, with measurements taken of various biochemical parameters. Results showed that FEU could increase reduced glutathione (GSH) levels, GSH/oxidized glutathione (GSSG) ratio, superoxide dismutase (SOD) and catalase (CAT) activities, decrease xanthine oxidase (XO) activities, GSSG, malondialdehyde (MDA) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels. The finding of the study suggests that FEU possess protective effects against exhaustive exercise-induced oxidative stress and oxidative injury, which might be important in preventing loss of cellular function and warrants quick recovery after sports competition.

Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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Volume Title
Proceedings of the International Conference on Chemical, Material and Food Engineering
Series
Advances in Engineering Research
Publication Date
July 2015
ISBN
10.2991/cmfe-15.2015.5
ISSN
2352-5401
DOI
10.2991/cmfe-15.2015.5How to use a DOI?
Copyright
© 2015, the Authors. Published by Atlantis Press.
Open Access
This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

risenwbib
TY  - CONF
AU  - JinYang Lin
AU  - ZhuoYing Zhang
PY  - 2015/07
DA  - 2015/07
TI  - The Effects of Flavonoids from Eucommia Ulmoides on Body's Antioxidant Systems, Lipid Peroxidation and Oxidative DNA Damage after Exhaustive Exercise
BT  - Proceedings of the International Conference on Chemical, Material and Food Engineering
PB  - Atlantis Press
SP  - 19
EP  - 22
SN  - 2352-5401
UR  - https://doi.org/10.2991/cmfe-15.2015.5
DO  - 10.2991/cmfe-15.2015.5
ID  - Lin2015/07
ER  -